Hormonal and Metabolic Regulation of Cardiac Function

Question 1

Regarding hormonal control of cardiac function (true or false):

Endogenous noradrenaline has greater potency at α1-receptors than adrenaline

Answer 1

True

Question 2

Regarding hormonal control of cardiac function (true or false):

α1 activation is associated with vasodilatation

Answer 2

False. α1 activation is associated with vasoconstriction.

Question 3

Regarding hormonal control of cardiac function (true or false):

Endogenous noradrenaline has greater potency at β-receptors than adrenaline

Answer 3

False. Adrenaline has greater potency at these receptors.

Question 4

Regarding hormonal control of cardiac function (true or false):

β1-receptors mediate an increase in heart rate and contractility

Answer 4

True

Question 5

Regarding hormonal control of cardiac function (true or false):

β2-receptors mediate vasoconstriction

Answer 5

False. β2-receptors mediate vasodilatation.

Question 6

Regarding metabolic factors which regulate cardiac function (true or false):

Hypocalcaemia is associated with QT shortening

Answer 6

False. Hypocalcaemia is associated with QT prolongation.

Question 7

Regarding metabolic factors which regulate cardiac function (true or false):

Hyperkalaemia is associated with widening of the PR interval

Answer 7

True

Question 8

Regarding metabolic factors which regulate cardiac function (true or false):

Intracellular acidosis improves myocardial contractility

Answer 8

False. Intracellular acidosis is associated with reduced contractility.

Question 9

Regarding metabolic factors which regulate cardiac function (true or false):

Heart rate increases by 10 bpm for every 1°C rise in temperature

Answer 9

True

Question 10

Regarding metabolic factors which regulate cardiac function (true or false):

Prolonged elevation of temperature is associated with increased myocardial contractility

Answer 10

False. Prolonged elevation of temperature is associated with reduced contractility.