HomeStretch CRACK Physics NUCS Flashcards
Isobaric transition means?
No change in mass (like a barbell)
beta minus decay
neutron excess (proton deficient)
changes neutron to proton and emits a beta particle - isobaric transition
e- emission can damage DNA - basis of radionucleotide therapy
alpha decay
heavy unstable atoms
lots of tissue damage
Beta Positive decay
Proton excess (neutron deficient) [rival of e- capture]
has at least 1.02MeV
positron emission, leading to two 511 keV photons which fly 180 degrees apart
e- capture
proton excess (neutron deficient) [rival of beta + decay]
Does not require 1.02 MeV
Leads to gamma emission and characteristic radiation
GIT! Gallium, indium and thalliam decay this way. . .
Cyclotron produce radioisotopes
Moly-99
F-18
Ga-67
Tl-201
Reactor produced radioisotopes
Moly-98 (which can then be placed in a cyclotron to make moly-99)
I-131
Xenon-133
Tl-201
Generator produced radionuclides
Tech-99m (from cyclotron produced Moly-99, which was made from reactor produced moly-98)
Krypton-81m (from cyclotron rubidium-81)
The NRC allows what moly99 to tech99m ratio in the ______ purity test
0.15 micro Ci of Mo to 1 milli Ci of Tech-99m in the radionuclide chemical test at the time of administration
Chemical purity test
Limit/number?
What do you see in a liver/spleen scan if this is not correct?
How about in other scans?
the chemical = aluminum!
performed with a pH paper
the allowed amount is < 10 microgram of Al / 1 mL
Liver/spleen scan + LUNG = Al contamination
Tc scan + LIVER activtiy = Al contamination
Radiochemical purity test
Limits
radiochemical = free tech99m!
thin-layer chromatography is used to test for this
95% Na99mTcO4
92% for 99mTc Sulfor colloid MAA
91% for all other Tc radiopharmaceuticals
What radioisotopes use collimator:
Low energy
Medium Energy
High energy
Low (1-200keV) = Tech99m, I123, Xe133, TI 201
Medium (200-400keV) = Ga67, In111
High (>400) = I131
Field uniformity recommended counts for both extrinsic and intrinsic range?
5-10 million
QA intervals for:
Field uniformity (external and internal) (and limit)
Energy window
Image linearity and spatial resolution
Center of rotation
- Field uniformity (external and internal)
- external (with collimator) = daily
- internal (without collimator) = weekly
- 2-5% non-uniformity is allowed (1% if SPECT!)
- Energy window = DAILY
- Image linearity and spatial resolution = WEEKLY
- Center of rotation = MONTHLY
Maximum dose a GM counter can handle before goes into dead time?
100 mR/h