Homeostasis and the skeletal system Flashcards

1
Q

What is an example of positive feedback?

A

Increasing muscle contraction during childbirth

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2
Q

what division of skeleton highlights the arm, shoulder, pelvis, leg bones?

A

appendicular skeleton

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3
Q

How does the proximal epiphysis lie to the articular cartilage

A

distal

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4
Q

Major Functions of bone

A

Support (tendon attachment), protection, assistance in movement, mineral storage and release and blood cell production

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5
Q

Bone Formation

A
  1. Calcium released from bone.
  2. Indirectly triggers osteoblast differentiation.
  3. Preosteoblasts mature into osteoblasts.
  4. Osteoclasts lay down bone.
  5. Expression of RANKL
  6. Inactive osteoclasts express RANK
  7. RANKL binds to RANK
  8. Activates osteoclasts.
  9. Bone resorbed.
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6
Q

Compact bone is also known as

A

Cortical bone

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7
Q

Osteoclast matches with

A

RANK

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8
Q

Osteoblast matches with

A

RANKL

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9
Q

mechanism for osteoblast regulation

A

WNT, Runx2, Osterix, TNF-a, OPG

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10
Q

when an individual begins exercise, their muscles promote more…

A

venous return

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11
Q

more venous return, increase the…

A

stroke volume

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12
Q

the sudden demand on the body causes an increase in…

A

sympathetic nervous system activity

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13
Q

increase in symp nervous system activity, does what to heart rate?

A

increases the heart rate

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14
Q

increasing the heart rate then…

A

increases the cardiac output

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15
Q

once the demand has passed, parasymp activity does what to the heart rate?

A

reduces the heart rate

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16
Q

what does MSC stand for

A

mesenchymal stem cell

17
Q

the best example of an integrating centre in homeostasis

A

Hypothalamus

18
Q

what are the mechanosensors of bone?

A

Canaliculi

19
Q

what is the term for ‘eating’ or ‘destroying’ bone

A

resorb

20
Q

an osteon contains…

A

blood vessels centrally

21
Q

concentric lamellae contains…

A

blood vessels peripherally

22
Q

What feedback loop is blood clotting

A

Positive

23
Q

what feedback loop is parturition

A

positive

24
Q

what feedback loop is regulation of ventilation

A

negative

25
Q

what feedback loop is glucose regulation

A

negative

26
Q

what term best defines transient physiological modifications in homeostasis

A

acclimatisation

27
Q

Sequence of actions in response to a painful stimulus in homeostasis

A
  1. Stimulus
  2. Nociceptor
  3. Afferent pathway along a…
  4. Sensory neuron
  5. Integration center
  6. Efferent pathway along a…
  7. Motor neuron
  8. Muscle
28
Q

is wound healing an example of homeostasis within normal limits

A

no

29
Q

what lines compact bone

A

periosteum

30
Q

which part of the body is the popliteal associated with

A

knee

31
Q

do osteoclasts resorb bone

A

yes

32
Q

which one is not a connective tissue:
blood
bone
cartilage
simple squamous epithelia
adipose tissue

A

simple squamous epithelia

33
Q

whats the correct order of the following layers of the growth plate from diaphysis to epiphysis:
1. Calcified cartilage 2. Hypertrophic cartilage 3. Proliferating cartilage 4. Resting cartilage

A

1,2,3,4