homeostasis and response - HOMEOSTASIS Flashcards

thermoregulation, body temperature, losing/gaining heat, sugar regulation, blood glucose + controlling it, diabetes, osmoregulation/ADH, kidney transplants, hormones/puberty in females

1
Q

TR
core body temperature

A

vital organs deep in the body like liver, kidneys, heart are maintained at 37 degrees C
(70% of your energy is used to keep this up)

skin temperature at body extremities (toes, fingers) are usually lower than core body temp

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2
Q

TR
more or less tired on a cold day?

A

on a cold day, you’d be focusing your energy on generating more heat so you’d be more tired and hungry

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3
Q

TR
how can heat be gained

A
  • movement and exercise
  • shivering
  • vasoconstriction (turning blue)
  • wearing extra clothes
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4
Q

TR
how can heat be lost

A
  • sweating
  • vasodilation (turning red)
  • removing extra clothing
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5
Q

TR
how is temperature controlled (receptors, hypothalamus)

A

body temp is monitored and controlled by temperature receptors in the skin & brain
–> they detect changes in the temperature of blood flowing through those areas

the thermoregulatory centre is in the brain
if body temp deviates from 37 degrees C:

the hypothalamus & skin receptors send out electrical signals
these trigger actions or behaviour that increase or decrease heat loss

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6
Q

TR
why do we shiver/get goosebumps

A

when core body temperature drops, muscles begin to twitch (rapidly contract and relax) –> shivering
shivering generates heat which raises body temperature

goosebumps involuntarily appear when someone becomes cold
they are caused by tiny muscles at the base of body hairs pulling the hairs erect
the upright hairs trap an insulating layer of air which helps reduce heat loss

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7
Q

TR
vasoconstriction/warming up
why do people go pale when cold?

A

when core body temperature falls, blood vessels in the skin get narrower - vasoconstriction
–> this reduces the volume of blood flowing near the skin surface so blood runs deeper and reduces the amount of heat loss from the body

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8
Q

TR
vasodilation/cooling down
why do people turn red when hot?

A

when core body temperature rises, blood vessels in the skin get wider - vasodilation
–> this allows a larger volume of blood to flow near the surface of the skin, transferring heat to the environment and cooling the body down

additional cooling occurs with production of sweat from sweat glands –> as sweat evaporates, it transfers heat away from the body

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9
Q

TR
negative feedback control of body temperature

A

BODY TEMP FALLS

skin sensory nerve endings stimulated
hypothalamus detects change in blood temperature

impulse sent to muscles and skin

shivering (muscle contraction, increased metabolism and relaxation) and vasoconstriction begin

BODY TEMP RISES

skin sensory nerve ending stimulated
hypothalamus detects change in blood temperature

impulse sent to muscles and skin

sweating (losing water through pores in skin to cool by evaporation) and vasodilation begin

BODY TEMP FALLS…..

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10
Q

homeostasis meaning

A

the process of keeping things the same
a series of automatic control systems ensures that the body maintains a constant temperature and steady levels of water, ions, and blood sugar.

homeostasis allows the body’s cells to work at their optimum

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11
Q

glucose

A

a type of sugar used by the body to provide energy

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12
Q

glycogen

A

a storage substance made of glucose stored in the liver

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13
Q

insulin

A

a hormone (chemical messenger) that tells your body to change glucose –> glycogen
made in the pancreas

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14
Q

glucagon

A

a hormone that tells your liver to change glycogen BACK –> glucose
made in the pancreas

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15
Q

what affects blood glucose

A
  • eating - rise
  • vigorous exercise - fall
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16
Q

dangers of high/low blood glucose

A

excess glucose - makes blood plasma and tissue fluid around cells TOO CONCENTRATED
–> this can severely damage cells e.g. causing crenation (collapsing) in red blood cells

low blood sugar can make cells swell up and burst - lysis

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17
Q

negative feedback controlling blood glucose levels

A

BLOOD GLUCOSE LEVELS RISE

Pancreas realises that glucose levels are too high

Pancreas releases insulin (chemical messenger) towards Liver through the bloodstream

Liver receives the message so decreases levels of glucose in blood by taking glucose molecules from the bloodstream and sticking it together* to create glycogen
Liver stores it

*takes a soluble molecule that affects osmosis - sticks it together - creates an insoluble molecule that doesn’t affect osmosis

BLOOD GLUCOSE LEVELS FALL

Pancreas realises that the glucose levels are now too low

Pancreas releases glucagon (chemical messenger) through the bloodstream to Liver

Liver receives the message so takes the stored glycogen and splits it up into glucose again and releases it into the bloodstream to increase the blood glucose levels

BLOOD GLUCOSE LEVELS RISE…

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18
Q

type 1 diabetes
- symptoms and treatment

A

pancreas unable to produce insulin

symptoms:
- frequent urination
- thirst
- fatigue
- confusion
- collapse

treatment
- control
- frequent blood sugar testing
- high sugar –> inject insulin
- stem cell transplant

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19
Q

type 2 diabetes
- treatment

A

liver/muscles no longer recognise insulin produced by pancreas

treatment:
- older people - treated with tablets
- metformin persuades liver/muscles to recognise insulin
- regular exercise + healthy diet
- lifestyle change

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20
Q

where do you gain and lose water

A

gain
- respiration in cells (350cm^3)
- drinks (1450cm^3)
- food (800cm^3)

loss
- faeces (100cm^3)
- exhaled air (400cm^3)
- sweat (600cm^3)
- urine (1500cm^3)

21
Q

what is the job of the kidney

A

to balance the amount of water it takes in with the amount it gets rid of

22
Q

what happens when you don’t drink enough water

A

in hot weather
- lose water as sweat to keep you cool
- kidney produces small amounts of concentrated urine using less water in the body
- you become thirsty to increase water consumption
- water levels then increase due to ADH and thirst

23
Q

what happens when you drink too much water

A
  • too much water in the body
  • use the toilet a lot
  • kidney produces a large volume of dilute urine
  • water levels decrease due to lots of urine and ADH
24
Q

what does the hormone ADH do

A

it controls the amount of water in your urine and is made by the pituitary gland in the brain when you need to keep water in your body

25
Q

when you are dehydrated how much ADH is released

A

more ADH is released and concentrated urine is produced

26
Q

when you are overhydrated how much ADH is released

A

less ADH is released and dilute urine is produced

27
Q

what are the 3 kidney stages (no explanation)

A

filtration
selective reabsorption
urine formation

28
Q

what is filtration in the kidneys (1)

A

the RENAL ARTERY branches and ends with lots of capillaries called the GLOMERULUS (inside the nephron).
as blood passes through each glomerulus, it is filtered.
due to HIGH PRESSURES, SMALL MOLECULES are filtered out of the glomerulus and blood and passed into the nephron

29
Q

what is selective reabsorption in the kidneys (2)

A

the kidneys SELECTIVELY REABSORBS molecules, only those which the body needs, back into the blood stream from the nephron.
this happens by active transport (energy from respiration is needed for reabsorption)

30
Q

what is urine formation in the kidneys (3)

A

the molecules which are NOT selectively reabsorbed (urea, excess water, ions) form your urine

31
Q

normal blood water levels increase… what happens next

A

receptors detect and pituitary gland releases less ADH
-
kidney reabsorbs less water. urine is more dilute
-
blood water levels reduce. decreased ADH secretion stops

32
Q

normal blood water levels decrease… what happens next

A

receptors detect and pituitary gland releases more ADH
-
kidney reabsorbs more water. urine is less dilute and more concentrated
-
blood water levels increase. increased ADH secretion stops

33
Q

where is a replacement kidney usually attached

A

it is usually placed in the groin and attached to the blood vessels and the bladder - the ureter carries urine from the new kidney to bladder

34
Q

what has to be special about the donor kidney and why

A

the kidney has to be very similar to to the patient’s tissue type because rejection is a major problem with transplantation.
the recipients immune system could recognise it as nonself and try to destroy it.

35
Q

how do you choose a patient for a kidney transplant

A

your tissue type is determined the antigens on the surface of every cell
the antigens on every kidney donor are analysed and matched with a similar recipient

36
Q

how do you reduce infection risk during kidney transplantation

A

immunosuppressant to prevent rejection however is weakens your immune system

37
Q

advantages/disadvantages of dialysis and transplantation

A

dialysis

DISADVANATAGE
- each session takes 6 - 10 hours and 3 times a week
- patients have to strictly restrict diet and fluids

transplant

ADVANTAGE
- majority of UK supports organ donation
- person can survive well with 1 kidney

DISADVANTAGE
- shortage of donors
- kidney must be transplanted within 12 hours
- rejection possibility
- have to:
imitate recipient’s bone marrow
do drug treatment
keep in sterile conditions
to minimise rejection risk

38
Q

when does puberty happen in males and females

A

testes make testosterone and this stimulates produce of sperm in boys

ovaries make oestrogen and start to release eggs in girls

39
Q

what changes happens to males and females during puberty

A

males
broader shoulders
hair on face/legs/genitals
enlarged genitalia
voice deepens
skin changes

girls
breasts develop
hips widen
hair
skin changes

40
Q

what are the 2 main things hormones do

A

stimulate egg release
inhibit egg release

41
Q

4 stages of menstruation

A

1 - lining of uterus breaks down and bleeding begins

2 - stretches from day 4 to 14, when lining is repaired

3 - on day 14, the egg is released from the ovary

4 - the maintenance stage where the uterus is maintained in case the egg is fertilised

42
Q

what are the 4 sets of hormones

A

follicle stimulating hormone (FSH)
oestrogen
luteinizing hormone (LH)
progesterone

43
Q

what is the hormone
- follicle stimulating hormone (FSH)
responsible for

A
  • it is made by the pituitary
  • stimulates the development of an ovum
  • stimulates ovaries to produce oestrogen
44
Q

what is the hormone
- oestrogen
responsible for

A
  • thickens the lining of the uterus
  • inhibits production of FSH
  • stimulates pituitary to produce LH
45
Q

what is the hormone
- luteinizing hormone (LH)
responsible for

A
  • produced by pituitary
  • stimulates the release of an egg
46
Q

what is the hormone
- progesterone
responsible for

A
  • carries on maintaining the endometrial lining of the uterus for a potential pregnancy
  • stops a new follicle developing
47
Q

negative feedback loop of the puberty hormones

A

FSH made by pituitary

–>

eggs GROW inside follicle

–>

oestrogen made by ovary stimulates the pituitary to make LH

–> oestrogen stops making FSH and the cycle restarts

OR!!!!!!!!!!!!!!!!!!!!!!!!!!!!!!!!!!!

–> lining of uterus thickens

LH made by pituitary

–>

progesterone made by ovary
- if pregnant, progesterone and oestrogen continue to be produces
- if not pregnant, progesterone production stops and menstruation occurs

cycle starts again

48
Q
A