Homeostasis Flashcards
Define homeostasis
- the maintenance of a constant internal environment
- process which ensures that composition of body fluids kept within narrow limits
Define internal environment
- refers to conditions within body of organism
- humans: blood and tissue fluids
- stable internal environment, allow organism to be independent from changes in external environment/surroundings
Why does body temp need to be kept constant?
- environmental conditions in surroundings constantly changing
- enzymes in body can only work in specific range of temp
- change in body temp may lead to enzyme inactivation or denaturation
- high fever thus fatal
Why must tissue fluid be kept at constant pH and wp?
- drastic change in pH, affect enzyme reactions in cells, harm body
- drastic change in wp may cause cells to swell, burst; shrivel, affect reactions
- composition of tissue fluid need to kept within very narrow limits to ensure constant pH and wp
Homeostasis involves negative feedback
- in homeostatic control, body reacts to bring abt opposite effect to changes detected
- if system/body disturbed, disturbance sets in motion a sequence of event that tends to restore a system to original state (negative feedback process)
Receptors/sense organs
-organs/structures in body that detect changes in body condition
Negative feedback process
- norm/set pt to be maintained
- stimulus: change in internal environment e.g. condition rises/decreases below normal
- receptor: detect stimulus, send signal to control centre
- corrective mechanism: bring abt reverse effect of stimulus
- feedback to stimulus once set pt reached, corrective mechanism stops
Examples of homeostasis in humans
- regulating body temp
- regulating blood glucose conc
- regulating wp
Regulation of blood glucose conc
- glucose needed for cellular respiration, provide energy for vital activities
- blood normally contains 70-90 mg of glucose per 100cm3 of blood
when blood glucose lvl rises above normal lvl
- normal set pt
- stimulus: blood glucose lvl rises above normal
- receptor: islets of langerhans in pancreas stimulated (control centre)
- corrective mechanism: islets of Langerhans secrete insulin into bloodstream, blood transport insulin to liver and muscles
- insulin increases permeability of cell surface membrane to glucose, glucose absorbed more quickly
- insulin causes liver and muscles to convert excess glucose to glycogen
- glycogen stored in liver and muscles - blood glucose conc decreases, provides negative feedback to receptor to reduce insulin production
when blood glucose lvl falls below normal
- normal set pt
- stimulus: blood glucose falls below normal
- receptor: islets of Langerhans in the pancreas stimulated
- corrective mechanism: islets of Langerhans secrete glucagon into bloodstream, blood transports glucagon to liver and muscles
- glucagon causes conversion of stored glycogen back to glucose
- from liver, glucose enters bloodstream - negative feedback: blood glucose conc increases, provides feedback to receptor to decrease glucagon production
regulating blood water potential
- normal set pt
- stimulus: wp of blood increases/decreases (large intake of water/loss of water thru sweating)
- receptor: hypothalamus in brain stimulated
- corrective mechanism:
- less/more ADH (anitdiuretic hormone) released by pituitary gland into bloodstream
- less/more ADH transported to kidneys
- cells in wall of collecting ducts become less/more permeable to water
- less/more water absorbed into bloodstream
- more/less water excreted, more concentrated/dilute
Role of skin
- forms protective covering over body surface
- regulates temp and excretion
Structure of skin: Blood vessels (capillaries and arterioles) in dermis layer
- blood vessels are present in dermis layer
- constriction and dilation of arterioles caused by contraction of muscles in arteriole walls
- constriction and dilation of arterioles help to regulate body temp
- vasodilation vs vasoconstriction
Vasodilation
- dilation of arterioles
- more blood sent to blood capillaries in skin
- e.g. blushing/flushed after vigorous activities
- due to numerous blood vessels in skin dilating