Hodgkin Lymphoma -Krafts Flashcards
1
Q
Hodgkin Lymphoma
Things you must know!
A
-Younger patients, good prognosis
-Contiguous spread - can predict it
- 5 subtypes
- Reed-Sternberg cell (2 nuclei, very big)
2
Q
What is important for prognosis?
A
The stage and how far it has spread
The subtype doesn’t matter.
3
Q
Subtypes:
A
- Nodular lymphocyte-predominance Hodgkin lymphoma
- Classical Hodgkin lymphoma
- Nodular sclerosis
- Lymphocyte rich
- Mixed cellularity
- Lymphocyte depletion
4
Q
Nodular L-P Hodgkin Lymphoma
A
- Asymptomatic young male with cervical lymphadenopathy
- Good prognosis
- B-cell origin
- Popcorn cells
5
Q
Nodular Sclerosis Hodgkin Lymphoma
A
- Most common subtype
- Good prognosis
- Lacunar cells
6
Q
Mixed Cellularity Hodgkin Lymphoma
A
- Worse prognosis
- usually disseminated at presentation
Classic Reed-Sternberg cells
Mixture of background cells
7
Q
Lymphocyte-Rich Hodgkin Lymphoma
A
- Uncommon
- Usually localized at presentation
- Popcorn cells
8
Q
Lymphocyte Depletion Hodgkin Lymphoma
A
- Rare
- Often disseminated at presentation
- Classic Reed-Sternberg cells
Collagen or reticulin background
9
Q
Treatment and Prognosis of Hodgkin Lymphoma
A
- Surgery, chemo, radiation
- Prognosis depends on stage
Danger: second malignancies
