HLA types Flashcards

1
Q

HLA-A3

A

Haemochromatosis

HFE gene

Disorder of increased intestinal iron absorption can lead to total-body iron overload.

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2
Q

HLA-A-3101

A

Carbamazepine hypersensitivity (Europeans)

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3
Q

HLA-B1502

A

Carbamazepine sensitivity

Especially Han chinese

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4
Q

HLA B27

A

Ank Spon

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5
Q

HLA DR2

A

MS

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6
Q

HLA B51

A

Behcet’s

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7
Q

HLA B54 + MEFV

A

Sweet’s syndrome

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8
Q

HLA B5701

A

Abacavir sensitivity

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9
Q

HLA B5801

A

Allopurinol sensitivity

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10
Q

HLA DQ1

A

Narcolepsy

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11
Q

HLA B5801

A

Allopurinol DRESS syndrome

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12
Q

HLA DQ2 DQ8

A

Coeliac disease

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13
Q

HLA DR1

A

Bronchiectasis

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14
Q

HLA DR2

A

Narcolepsy
Goodpastures
SLE
MS

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15
Q

HLA DR3

A
Dermatitis herpetiformis
Sjogren's syndrome
PBC
AIH
SLE
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16
Q

HLA DR4

A

T1DM (also HLA DR3)

Rheumatoid arthritis

17
Q

HLA DRB1-0301

A

SLE

18
Q

HLA DRB1-04

A

Rheumatoid arthritis

GCA/PMR spectrum