HLA associations Flashcards
1
Q
HLA B27
A
Ank spond
2
Q
HLA DR15/DR2
A
Goodpasture’s
3
Q
HLA DR3
A
Graves and SLE
4
Q
HLA DR3/DR4
A
T1DM
5
Q
HLA DR4
A
RA
6
Q
PTPN22
A
Tyrosine phosphatase expressed in lymphocytes, associated with development of RA, SLE and T1DM
7
Q
CTLA4
A
Receptor for CD80/CD86 expressed by T cells, transmits inhibitory signal to control T cell activation. Assoicated with SLE, T1DM and AI thyroid disease