Histopath

Question 1

Gilbert’s disease

Answer 1

Bilirubin increases with FASTING

Reduced UDP glucuronyl transferase activity

Question 2

Courvoisiers law

Answer 2

If the gall bladder is palpable in a jaundiced patient, the cause is unlikely to be gallstones
(pancreatic cancer)

Question 3

Obstructive jaundice

Answer 3

Pale stools, dark urine
No bilirubin reaches GI tract –> pale stools and ABSENT UROBILINOGEN IN URINE
Reflux of conjugated bilirubin into blood –> into the urine, producing dark urine

Question 4

Alcoholic hepatitis

Answer 4

Ballooning of liver cells

MALLORY - DENK bodies

Question 5

Terlipressin

Answer 5

Oesophageal varices