HLA associations Flashcards by Emily Wilson

Q

systemic lupus erythematosus

A

HLA DR/W2, DR/W3 and HLA B8, HLA DR3

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Q

dermatomyositis herpetiformis

A

HLA B8/DR3

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Q

kaposi’s sarcoma

A

HLA DR5/DR2

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Q

chronic active hepatitis

A

HLA DR3

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Q

grave’s disease

A

HLA DR3

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Q

myaesthenia gravis

A

HLA DR3

HLA B8

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Q

Addinson’s disease

A

HLA DR3

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Q

Sjogren’s syndrome

A

HLA DR3

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Q

ideopathic membranous nephropathy

A

HLA DR3

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Q

goodpasture’s syndrome

A

HLA DR2

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Q

narcolepsy

A

HLA DR2

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Q

multiple sclerosis

A

HLA DR2

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Q

juvenile insulin dependant diabetes

A

HLA DR3, 4 (positive association), HLA-DR2 (negative association)

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Q

coeliac disease

A

HLA DQ2/8, DR3/7/11

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Q

idiopathic haemachromatosis

A

HLA A3/B14

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Q

schizophrenia

A

HLA A28

Q

Behcet’s disease

A

HLA B5

Q

IBD associated arthritis (UC)

A

HLA B5

Q

ankylosing spondylitis

A

HLA B27

Q

psoriatic arthropathy

A

HLA B27

Q

Retter’s disease

A

HLA B27

Q

Reactive arthritis (including Reiter’s)

A

HLA B27

Q

Rheumatoid arthritis

A

HLA DR4

Q

Hashimoto’s disease

A

HLA DR5 ?DR11

Q

Pernicious anaemia

A

HLA DR5

Q

subacute thyroiditis

A

HLA B35

Q

linkage equilibrium in nephrotic syndrome

A

HLA A1, B8, DR3

Q

acquired immunodeficiency syndrome

A

HLA A1, B8, DR3

Q

post partum thyroiditis

A

HLA DR4

Q

pemphigus vulgaris (among Ashkenazi jews)

A

HLA DR4

Q

psoriasis vulgaris

A

HLA-Cw6