Autoimmunity Flashcards by Emily Wilson

Q

Addison’s disease

A

self antigen to adrenal cells

autoantibody response

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Q

Autoimmune haemolytic anaemia

A

self antigen to RBC membrane proteins

autoantibody response

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Q

Goodpasture’s syndrome

A

self antigen to renal and lung basement membranes

autoantibody response

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Q

Hashimoto’s thyroiditis

A

self antigen to thyroid proteins

autoantibodies, T cell response

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Q

Grave’s disease

A

self antigen to TSH receptor

autoantibody response

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Q

Idiopathic thrombocytopenia

A

self antigen to platelet membrane proteins

autoantibody response

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Q

Insulin-dependant diabetes

A

self antigen to pancreatic beta cells

autoantibodies, T cell response

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Q

Myasthenia gravis

A

self antigen to acetylcholine receptors

autoantibody response

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Q

Pernicious anaemia

A

self antigen to intrinsic factor

autoantibody response

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Q

Post-streptococcal glomerulonephritis

A

self antigen to kidney

immune complex response

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Q

Spontaneous infertility

A

self antigen to sperm

autoantibody response

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Q

Ankylosing spondylitis

A

self antigen to vertebrae

immune complex response

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Q

Multiple sclerosis

A

self antigen to brain or white matter

autoantibodies, T cell response

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Q

Rheumatoid arthritis

A

self antigen to connective tissue, IgG

immune complex response

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Q

Scleroderma

A

self antigen to nuclei, heart, lung, GIT, kidney

autoantibody response

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Q

Systemic lupus erythrematosus

A

self antigen to DNA, nuclear proteins, RBCs

immune complex response