HIV Medications Flashcards

1
Q

What are the five main categories of HIV drugs?

A
  1. NRTIs
  2. NNRTIs
  3. PIs
  4. INSTIs
  5. Entry inhibitors
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2
Q

What are the three types of Entry Inhibitors?

A
  1. Fusion inhibitor
  2. CCR5 antagonist
  3. Post-Attachment inhibitor
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3
Q

What is enfuvirtide?

A

Fusion inhibitor

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4
Q

What is maraviroc?

A

CCR5 antagonist

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5
Q

What is ibalizumab?

A

Post-Attachment Inhbitor

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6
Q

What is the MOA of NRTIs?

A

Mimic human nucleotides and terminate chains when taken up by HIV reverse transcriptase

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7
Q

What is the MOA of NNRTIs

A

Bind a hydrophobic pocket of the p66 subunit of the HIV reverse transcriptase

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8
Q

What is emtricitabine?

A

NRTI

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9
Q

What is lamivudine?

A

NRTI

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10
Q

What is zidovudine?

A

NRTI

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11
Q

What is tonofovir DF?

A

NRTI

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12
Q

What is abacavir?

A

NRTI

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13
Q

What is tenofovir alafenamide?

A

NRTI

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14
Q

What is ripilvirine?

A

NNRTI

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15
Q

What is etravirine?

A

NNRTI

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16
Q

What is doravirine?

A

NNRTI

17
Q

What is efavirenz?

A

NNRTI

18
Q

What is nevirapine?

A

NNRTI

19
Q

What is Raltegravir?

A

INSTI

20
Q

What is Dolutegravir?

A

INSTI

21
Q

What is Lopinavir?

A

PI

22
Q

What is Fosamprenavir?

A

PI

23
Q

What is Darunavir?

A

PI

24
Q

What is Atazanavir?

A

PI

25
Q

What is Nelfinavir?

A

PI

26
Q

What is Ritonavir?

A

Boosting agent

27
Q

What is Cobicistat?

A

Boosting agent

28
Q

What is Descovy?

A

Tenofovir alafenamide (NRTI) + Emtricitabine (NRTI)

29
Q

What is Biktarvy?

A

Bictegravir (INSTI) + Tenofovir alafenamide (NRTI) + Emtricitabine (NRTI)

30
Q

What is Juluca?

A

Dolutegravir (INSTI) + Rilpivirine (NNRTI)

31
Q

What is Dovato?

A

Dolutegravir (INSTI) + Lamivudine (NRTI)