HIV drugs Flashcards

1
Q

Biktarvy

A

Bictegravir/Emtricitabine/TAF (preferred treatment with 2 NRTIs & 1 INSTI)

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2
Q

Triumeq

A

Dolutegravir/Abacavir/Lamivudine (preferred treatment with 2 NRTIs & 1 INSTI)

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3
Q

Dovato

A

Dolutegravir/Lamuvudine (1 NRTI & 1 INSTI)

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4
Q

TDF vs TAF what are the differences?

A

TDF has more renal and bone issues than the newer TAF form

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5
Q

Tivicay

A

Dolutegravir

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6
Q

Truvada

A

Emtricitabine/TDF (2 NRTIs)

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7
Q

Descovy

A

Emtricitabine/TAF

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8
Q

Isentress

A

Raltegravir

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9
Q

What is special about Triumeq

A

Contains abacavir and must test for HLA-B*5701

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10
Q

When should Dovato not be started?

A

Has only 2 drugs and should not be started if the HIV RNA > 500,000 or if there is a hepatitis B coinfection

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11
Q

What if someone is doing well but not on a preferred ART regimen?

A

Keep them on their current regimen

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12
Q

What do integrase inhibitors (INSTIs) end in?

A

tegravir

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13
Q

What should you not take with INSTIs?

A

Cations and INSTis do not go together

Take INSTI 2 hours before or 6 hours after Al, Mg products

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14
Q

What do protease inhibitors end in?

A

navir

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15
Q

What are PI boosters?

A

Ritonavir 100mg or cobicistat 150mg are boosters

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16
Q

What is maraviroc (Selzentry)?

A

CCR5 antagonist and must have tropism assay results to identify type of co-receptor

Not useful if CXCR4 or mixed (CXCR4/CCR5)

17
Q

What is enfuviritide (Fuzeon)?

A

Fusion inhibor

90 mg SC BID

18
Q

What drugs can be used for PrEP?

A

Truvada or Descovy

Do not start PrEP without a negative HIV test first

19
Q

What drugs can be used for PEP? When does it need to be started?

A

Need to be started within 72 hours of the exposure and requires 28 day treatment

Truvada
Tivicay (Dolutegravir)
Isentress (Raltegravir)

20
Q

Complera

A

Bictegravir/Emtricitabine/TAF

21
Q

Atripla

A

Efavirenz/TDF/Emtricitabine (not preferred, 2 NRTIs and 1 NNRTI)