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NAPLEX > Formula stuff > Flashcards

Formula stuff Flashcards

1
Q

Which weight do you use for all drugs when dosing if they are underweight?

A

Total body weight (TBW)

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2
Q

Which weight do you use for most drugs if they are normal weight or obese?

A

TBW

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3
Q

Which drugs do you use IBW for if they are normal or obese weight? What about AdjBW if they are obese what drug class?

A

IBW: Acyclovir, synthroid, aminophylline

AdjBW: Aminoglycosides

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4
Q

When weight is >20kg what is the formula for fluid needs?

A

1500mL + 20mL(weight in kg - 20)

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5
Q

What is 1 grain equal to

A

65 mg

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6
Q

what is specific gravity

A

g/mL

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7
Q

What is the normal ABG pH?

A

7.35-7.45

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8
Q

What defines respiratory and metabolic acid/alkolosis with pCO2 and HCO3?

A

Respiratory: pCO2 <35 alkalosis, pCO2 >45 acidosis

Metabolic: HCO3 > 26 alkalosis, HCO3 < 22 acidosis

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9
Q

How to calc anion gap?

A

Na - Cl - HCO3

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10
Q

ANC calculation

A

WBC x (%segs + % bands)/100

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11
Q

Risk equation

A

Risk = # of subjects in group with unfavorable event/ total # of subjects in group

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12
Q

Relative risk and RRR and ARR

A

RR= risk in treatment group/ risk in control group

RRR= (% risk in control group - % risk in treatment group) / % risk in control group

ARR= (% risk in control group - % risk in treatment group)

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13
Q

NNT

A

1/ARR as a decimal

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14
Q

Insulin to carb ratio for rapid acting

A

Rule of 500 for rapid acting insulin

500/TDD (total daily dose) = grams of carbs covered by 1 unit of rapid acting

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15
Q

Insulin to carb ratio for regular insulin

A

rule of 450

450/TDD= grams of carbs covered by 1 unit of reglular

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16
Q

Correction factor for rapid insulin and for regular insulin

A

Rapid: 1800/TDD= CF for 1 unit of rapid acting insulin

Regular: 1500/TDD= CF for 1 unit of regular

17
Q

Correction Dose for insulin

A

CD= (BG now - BG target) / CF

18
Q

Friedewald equation

A

LDL = TC - HDL - TG/5

Not valid when TG > 400

19
Q

Minimum weighable quantity (MWQ)

A

Sensitivy requirement / 0.05 = MWQ

20
Q

BSA

A

BSA= square root of [ Ht (cm) x Wt (kg) / 3600 ]

21
Q

Bioavailability

A

F(%) = 100 x AUCextra / AUCintra x DOSEintra / DOSEextra

extravascular and intravascular

22
Q

Volume of distribution

A

VD = Amount of drug in body / concentration of drug in plasma

23
Q

Clearance

A

Cl = (F x Dose)/AUC

or

Cl=ke x Vd

24
Q

Elimination rate constant

A

ke = Cl/Vd

25
Q

Loading dose

A

LD = (Desired concentration x Vd) / F

26
Q

Phenytoin total correction for albumin

A

albumin < 3.5

Phenytoin corrected (mcg/mL) = Total phenytoin measured / (0.2 x albumin) + 0.1

Can also do for valproic acid

27
Q

KCl solution (oral) to tablets conversion

KCl 10% is what tablets

A

KCl 10% = 20 mEq/15 mL

28
Q

Calcium salts what % elemental calcium

Carb and citrate

A

carbonate 40%

Citrate 21%

29
Q

Aminophylline to Theophylline conversion

A

ATM (amin to theo multiple)

Amino to Theo x 0.8 so theo is stronger

30
Q

Loop diuretic potency

A

Furosemide 40mg
Torsemide 20mg
Bumetanide 1 mg

All are 1:1 IV: PO except furosemide is 1:2 so double PO dose from IV

31
Q

Metoprolol IV:PO conversion

A

1:2.5 IV:PO

32
Q

Iron elemental %

Ferrous sulfate

A

20% elemental iron so 325mg x 0.2 has 65 mg iron

33
Q

Insulin NPH dosed BID -> glargine dosed daily what is conversion?

Toujeo -> Lantus or Basaglar

A

NPH BID -> glargine QD (use 80% of NPH dose)

Toujeo -> Lantus/Basaglar (use 80% Toujeo dose)

34
Q

synthroid IV:PO dose conversion

A

IV:PO 0.75:1

35
Q

Steroid potency and equivalence

A

Cute Hot Pharmacists and Physicians Marry Together & Deliver Babies

Cortisone 25mg Methylprednisone 4mg
Hydrocortisone 20mg Triamcinolone 4mg
Prednisone 5mg Dexamethasone 0.75mg
Prednisolone 5mg Betamethasone 0.6mg

36
Q

Statin equivalence

A

Pharmacists Rock At Saving Lives and Preventing Fatty-deposits

Pitavastatin 2mg Lovastatin 40mg
Rosuvastatin 5mg Pravastatin 40mg
Atorvastatin 10mg Fluvastatin 80mg
Simvastatin 20mg

37
Q

Lithium conversions between syrup, mg, and mEq

A

5 mL = 300mg = 8 mEq

NAPLEX (6 decks)

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