HIV Drug Class

Question 1

Class of abacavir

Answer 1

Nucleoside reverse transcriptase inhibitor (NRTIs)

Question 2

Class of Lamivudine

Answer 2

Nucleoside reverse transcriptase inhibitor (NRTIs)

Question 3

Class of Zidovudine

Answer 3

Nucleoside reverse transcriptase inhibitor (NRTIs)

Question 4

Class of emtricitabine

Answer 4

Nucleoside reverse transcriptase inhibitor (NRTIs)

Question 5

Class of Tenofovir

Answer 5

Nucleotide reverse transcriptase inhibitor (NRTIs)

Question 6

NRTI combination products

Answer 6

Emtricitabine always comes with Tenofovir (Both Gilead)

Lamivudine comes with Abacavir / Zidovudine (Both GSK)

Question 7

Class of Etravirine

Answer 7

Non-nucleotide reverse transcriptase inhibitor (NNRTIs)

Question 8

Class of efavirenz

Answer 8

Non-nucleotide reverse transcriptase inhibitor (NNRTIs)

Question 9

Class of nevirapine

Answer 9

Non-nucleotide reverse transcriptase inhibitor (NNRTIs)

Question 10

Class of rilpivirine

Answer 10

Non-nucleotide reverse transcriptase inhibitor (NNRTIs)

Question 11

Class of atazanavir

Answer 11

Protease inhibitors (PIs)

Question 12

Class of darunavir

Answer 12

Protease inhibitors (PIs)

Question 13

Class of ritonavir

Answer 13

Protease inhibitors (PIs)

Question 14

Combination product of ritonavir

Answer 14

Kaletra = Lopinavir/Ritonavir

Question 15

Combination product of darunavir

Answer 15

Prezcobix = Darunavir/Cobicistat

Question 16

Class of raltegravir

Answer 16

Integrase inhibitors (INSTIs)

Question 17

Cass of dolutegravir

Answer 17

Integrase inhibitors (INSTIs)

Question 18

Class of elvitegravir (only in combination with cobicistat, TAF, emtricitabine)

Answer 18

Integrase inhibitors (INSTIs)

Question 19

Class of bictegravir (only in combination with emtricitabine, TAF)

Answer 19

Integrase inhibitors (INSTIs)

Question 20

Class of Maraviroc

Answer 20

CCR5 antagonist

Question 21

Recommended initial regimens for most people with HIV

Answer 21

1 Integrase inhibitors (INSTIs) + 2 NRTIs

Question 22

Common SE of Integrase inhibitors (INSTIs)

Answer 22

Nausea, headache, diarrhoea

Question 23

Common SE of protease inhibitors (PIs)

Answer 23

HyperG
Hyperlipidemia (except ATV)
LFT Increase
GI upset (n/v/d)
Rash

Question 24

SE of tenofovir

Answer 24

GI (n/v/d)

Renal fanconi syndrome

Question 25

SE of abacavir

Answer 25

Hypersensitivity, Rash

Need HLA-B*5701 screening before use

Question 26

SE of emtricitabine

Answer 26

Headache, diarrhea

Question 27

SE of lamivudine

Answer 27

n/v

Question 28

SE of zidovudine

Answer 28

Marrow suppression

Question 29

Common SE of Non-nucleotide reverse transcriptase inhibitor (NNRTIs)

Answer 29

Rash, SJS

GI (n/v/d)

Question 30

Which Non-nucleotide reverse transcriptase inhibitor (NNRTIs) may cause CNS SE?

Answer 30

Efavirenz –> take in empty stomach + nocte