HIV Drug Class Flashcards

1
Q

Class of abacavir

A

Nucleoside reverse transcriptase inhibitor (NRTIs)

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2
Q

Class of Lamivudine

A

Nucleoside reverse transcriptase inhibitor (NRTIs)

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3
Q

Class of Zidovudine

A

Nucleoside reverse transcriptase inhibitor (NRTIs)

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4
Q

Class of emtricitabine

A

Nucleoside reverse transcriptase inhibitor (NRTIs)

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5
Q

Class of Tenofovir

A

Nucleotide reverse transcriptase inhibitor (NRTIs)

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6
Q

NRTI combination products

A

Emtricitabine always comes with Tenofovir (Both Gilead)

Lamivudine comes with Abacavir / Zidovudine (Both GSK)

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7
Q

Class of Etravirine

A

Non-nucleotide reverse transcriptase inhibitor (NNRTIs)

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8
Q

Class of efavirenz

A

Non-nucleotide reverse transcriptase inhibitor (NNRTIs)

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9
Q

Class of nevirapine

A

Non-nucleotide reverse transcriptase inhibitor (NNRTIs)

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10
Q

Class of rilpivirine

A

Non-nucleotide reverse transcriptase inhibitor (NNRTIs)

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11
Q

Class of atazanavir

A

Protease inhibitors (PIs)

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12
Q

Class of darunavir

A

Protease inhibitors (PIs)

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13
Q

Class of ritonavir

A

Protease inhibitors (PIs)

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14
Q

Combination product of ritonavir

A

Kaletra = Lopinavir/Ritonavir

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15
Q

Combination product of darunavir

A

Prezcobix = Darunavir/Cobicistat

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16
Q

Class of raltegravir

A

Integrase inhibitors (INSTIs)

17
Q

Cass of dolutegravir

A

Integrase inhibitors (INSTIs)

18
Q

Class of elvitegravir (only in combination with cobicistat, TAF, emtricitabine)

A

Integrase inhibitors (INSTIs)

19
Q

Class of bictegravir (only in combination with emtricitabine, TAF)

A

Integrase inhibitors (INSTIs)

20
Q

Class of Maraviroc

A

CCR5 antagonist

21
Q

Recommended initial regimens for most people with HIV

A

1 Integrase inhibitors (INSTIs) + 2 NRTIs

22
Q

Common SE of Integrase inhibitors (INSTIs)

A

Nausea, headache, diarrhoea

23
Q

Common SE of protease inhibitors (PIs)

A
HyperG
Hyperlipidemia (except ATV)
LFT Increase
GI upset (n/v/d)
Rash
24
Q

SE of tenofovir

A

GI (n/v/d)

Renal fanconi syndrome

25
SE of abacavir
Hypersensitivity, Rash | Need HLA-B*5701 screening before use
26
SE of emtricitabine
Headache, diarrhea
27
SE of lamivudine
n/v
28
SE of zidovudine
Marrow suppression
29
Common SE of Non-nucleotide reverse transcriptase inhibitor (NNRTIs)
Rash, SJS | GI (n/v/d)
30
Which Non-nucleotide reverse transcriptase inhibitor (NNRTIs) may cause CNS SE?
Efavirenz --> take in empty stomach + nocte