HIV antiretroviral meds Flashcards
1
Q
HIV fusion inhibitor by binding gp41
A
Enfuvirtide
2
Q
HIV CCR5 antagonist (inhibits entry by blocking gp120 allosteric interaction)
A
Maraviroc
3
Q
integrase inhibitors (inhibits HIV DNA integration into host genome)
A
Dolutegravir
Raltegravir
4
Q
Atazanavir
darunavir
indinavir
ritonavir
A
inhibits HIV polyprotein cleavage
5
Q
Efavirenz
nevirapine
A
NNRTI (RT inhibitor—-inhibits HIV DNA synthesis from RNA template by terminating DNA chain elongation)
6
Q
Tenofovir
emtricitabine
lamivudine
abacavir
zidovudine
A
NRTI (competitive RT inhibitor)
7
Q
risk of infection with ____ when CD4+ count is <200
A
Pneumocystis jirovecii
8
Q
risk of infection with ____ when CD4+ count is <100
A
Toxoplasma gondii
9
Q
risk of infection with ____ when CD4+ count is <50
A
MAC (mycobacterium avium complex)
