Hep B serological markers

Question 1

detectable during acute infection
(persistence >6 months=chronic infection)

hep B virus surface glycoproteins

Answer 1

HBsAg

Question 2

detectable during acute infection
indicates increased in viral replication and infectivity

hep B virus polypeptide

Answer 2

HBeAg

Question 3

detectable during acute infection
present during window phase

Answer 3

Anti-HBc IgM

Question 4

seen w/ cleared infection or vaccination
(confers long term immunity)

Answer 4

Anti-HBs

Question 5

develop in cleared infection and later in chronic infection

indicates decreased viral replication and infectivity

Answer 5

Anti-HBe

Question 6

present in both acute and chronic infection

not present after vaccination

Answer 6

Anti-HBc IgG