HIV Flashcards
What type of infection is HIV?
Systemic, persistent
What Baltimore classification does HIV come under?
Class VI
What receptors does HIV bind to?
CD4 receptor (using the GP120 protein)
How does it enter the cell?
R-M endocytosis
Where in the cell does reverse transcription occur?
In the cytoplasm
Why doesn’t HIV carry RdRp with its genome?
Doesn’t need to! It hijacks the host machinery (after integration into host chromosomes) for transcription and translation
Modes of transmission.
Unprotected sexy times ;) and blood borne
How does HIV present clinically?
Flu-like symptoms for 4-6 weeks (muscle aches, fever, coughing, being gross, etc)
How is HIV treated?
Lots of anti-virals forever :( $$$ (HARRT therapy)
When do you go from having HIV to AIDS?
When your CD4 levels drop below 200
What virus family does HIV come from?
Retroviridae
Where does HIV bud from?
Plasma membrane
