HIV

Question 1

HIV screening

Answer 1

⭐️ Combination antigen/antibody test (100% sensitive)
Or 2️⃣: ELISA “antibody only test”

Question 2

HIV confirmatory test

Answer 2

⭐️ HIV-1/HIV-2 antibody differentiation immunoassay
Or 2️⃣: Western blot

Question 3

AIDS

Answer 3

CD4 cell count <200 or
AIDS-defined disease»
1. PCP (CD4 <200) » TMP-SMX
2. CNS lymphoma (CD4 <100)
3. Toxoplasmosis (CD4 <100)
4. Cryptococcal meningitis (CD4 <100)
5. CMV retinitis (CD4 <50)
6. MAC (CD4 <50) » macrolide

Question 4

HIV primary CNS lymphoma vs Toxoplasomsis

Answer 4

Contrast CT
🔹Solitary ring-enhancing lesion = lymphoma
🔹Multiple ring-enhancing lesion = toxo

Question 5

Any HIV patient with CD4<200 need to be started on […] prophylaxis

Answer 5

TMP-SMX

Question 6

Any HIV patient with CD4<50 need to be started on […] prophylaxis

Answer 6

Macrolide + Ethambutol

Question 7

HIV treatment

Answer 7

2 NRTIs + […] “zidovudine, lamivudine”
-NNRTI
-Protease inhibitor “-avir”
-Nucleotide analogs