HIV Flashcards

1
Q

HIV drugs that work in stage 1 : binding/attachment

A

maraviroc (Selzentry)

ibalizumab-uiyk (Trogarzo)

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2
Q

HIV drugs that working in stage 2: fusion

A

enfuvirtide (Fuzeon)

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3
Q

HIV drugs that working in stage 3: reverse transcription

A

NNRT

NRTI

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4
Q

HIV drugs that working in stage 4: integration

A

INSTi

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5
Q

HIV drugs that working in stage 7: budding and maturation

A

protease inhibitors

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6
Q

HIV agents one-pill, once-daily

A

Biktarvy
Triumeq
Dovato

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7
Q

Biktarvy

A

bictegravir
emtricitabine
TAF

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8
Q

Triumeq

A

dolutegravir
abacavir
lamivudine

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9
Q

Dovato

A

dolutegravir

lamivudine

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10
Q

Truvada

A

emtricitabine

TDF

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11
Q

Descovy

A

emtricitabine

TAF

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12
Q

Tivicay

A

dolutegravir

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13
Q

Isentress

A

raltegravir

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14
Q

PrEP agents

A

Truvada

Descovy

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15
Q

PEP agent

A

Truvada

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16
Q

Stribild

A

elvitegravir
cobicistat
emtricitabine
TDF

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17
Q

Genvoya

A

elvitegravir
cobicistat
emtricitabine
TAF

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18
Q

Atripla

A

efavirenez
emtricitabine
TDF

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19
Q

Odefsey

A

emtricitabine
rilpivrine
TAF

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20
Q

Symfi

A

efavirenz
lamivudine
TDF

21
Q

Epzicom

A

abacavir

lamivudine

22
Q

NRTi

A

tenofovir disoproxil fumarate

tenofovir alafenamide

lamivudine

emtricitabine

abacavir

zidovudine

didanosine

stavudine

23
Q

integrase strand transfer inhibitors (INSTIs)

A

-end in tegravir

bictegravir

elvitegravir

dolutegravir

raltegravir

24
Q

Protease inhibitors

A
  • end in -nevir

atazanvir

darunavir

fosamprenavir

indinavir

lopinavir + ritonavir

saquinavir

tipranavir

25
enhancers
ritonavir cobicistat
26
NRTi that does NOT need renal dose adjustment
Abacavi
27
NRTi used in labor and delivery when mother's viral load is >1000 copies/ml
IV Zidovudine
28
NRTI BOXED warning
lactic acidosis severe hepatomegaly with steatosis
29
NRTi NOT used to treat both HIV/HBV
abacavir
30
Allele screening for abacavir
HLA-B*5701
31
Warning and side effect for zidovudine
myopathy neutropenia anemia
32
NRTI that have a warning for lipodystrophy
stavudine didanosine zidovudine
33
Side effects for all NRTI
nausea diarrhea
34
Warning for TDF/AF
Nephrotoxicity Osteoporosis Fanconi Syndrome
35
Cations that cannot be taken at the same time as INSTI
Aluminum Magnesium
36
NNRTi
efavirenz rilpivirine doravirine nevirapine etravirine delavidine
37
Rilpivirine and food
must be taken with a full meal; no protein drink subsitution
38
Efavirenz and food
take on a empty stomach at bedtime
39
Boxed warning for all NNRTi
hepatotoxicity with severe rash
40
Contraindication for rilpivirine
use with PPI (drug absorption is acid-dependent)
41
Warning/side effect for rilpivirine
depression insomnia QT prolongation
42
PI taken without food
fosamprevair oral solution
43
Do NOT take Kaletra and ritonavir with __ __ or __
metronidazole tinidazole disulfram
44
PI caution with sulfa allergy
darunavir fosamprenavir tipranavir
45
fosamprenvir may cause ___ in patient's with a sulfa allergy
hemolytic anemia
46
CrCl cutoff for Stribild
<50; do not use
47
CrCl cut off for Genvoya
<30; do not use
48
Maraviroc only works with __ ___ disease.
CCR-5 tropic