HIV

Question 1

HIV drugs that work in stage 1 : binding/attachment

Answer 1

maraviroc (Selzentry)

ibalizumab-uiyk (Trogarzo)

Question 2

HIV drugs that working in stage 2: fusion

Answer 2

enfuvirtide (Fuzeon)

Question 3

HIV drugs that working in stage 3: reverse transcription

Answer 3

NNRT

NRTI

Question 4

HIV drugs that working in stage 4: integration

Answer 4

INSTi

Question 5

HIV drugs that working in stage 7: budding and maturation

Answer 5

protease inhibitors

Question 6

HIV agents one-pill, once-daily

Answer 6

Biktarvy
Triumeq
Dovato

Question 7

Biktarvy

Answer 7

bictegravir
emtricitabine
TAF

Question 8

Triumeq

Answer 8

dolutegravir
abacavir
lamivudine

Question 9

Dovato

Answer 9

dolutegravir

lamivudine

Question 10

Truvada

Answer 10

emtricitabine

TDF

Question 11

Descovy

Answer 11

emtricitabine

TAF

Question 12

Tivicay

Answer 12

dolutegravir

Question 13

Isentress

Answer 13

raltegravir

Question 14

PrEP agents

Answer 14

Truvada

Descovy

Question 15

PEP agent

Answer 15

Truvada

Question 16

Stribild

Answer 16

elvitegravir
cobicistat
emtricitabine
TDF

Question 17

Genvoya

Answer 17

elvitegravir
cobicistat
emtricitabine
TAF

Question 18

Atripla

Answer 18

efavirenez
emtricitabine
TDF

Question 19

Odefsey

Answer 19

emtricitabine
rilpivrine
TAF

Question 20

Symfi

Answer 20

efavirenz
lamivudine
TDF

Question 21

Epzicom

Answer 21

abacavir

lamivudine

Question 22

NRTi

Answer 22

tenofovir disoproxil fumarate

tenofovir alafenamide

lamivudine

emtricitabine

abacavir

zidovudine

didanosine

stavudine

Question 23

integrase strand transfer inhibitors (INSTIs)

Answer 23

-end in tegravir

bictegravir

elvitegravir

dolutegravir

raltegravir

Question 24

Protease inhibitors

Answer 24

• end in -nevir

atazanvir

darunavir

fosamprenavir

indinavir

lopinavir + ritonavir

saquinavir

tipranavir

Question 25

enhancers

Answer 25

ritonavir

cobicistat

Question 26

NRTi that does NOT need renal dose adjustment

Answer 26

Abacavi

Question 27

NRTi used in labor and delivery when mother’s viral load is >1000 copies/ml

Answer 27

IV Zidovudine

Question 28

NRTI BOXED warning

Answer 28

lactic acidosis

severe hepatomegaly with steatosis

Question 29

NRTi NOT used to treat both HIV/HBV

Answer 29

abacavir

Question 30

Allele screening for abacavir

Answer 30

HLA-B*5701

Question 31

Warning and side effect for zidovudine

Answer 31

myopathy

neutropenia

anemia

Question 32

NRTI that have a warning for lipodystrophy

Answer 32

stavudine

didanosine

zidovudine

Question 33

Side effects for all NRTI

Answer 33

nausea

diarrhea

Question 34

Warning for TDF/AF

Answer 34

Nephrotoxicity

Osteoporosis

Fanconi Syndrome

Question 35

Cations that cannot be taken at the same time as INSTI

Answer 35

Aluminum

Magnesium

Question 36

NNRTi

Answer 36

efavirenz

rilpivirine

doravirine

nevirapine

etravirine

delavidine

Question 37

Rilpivirine and food

Answer 37

must be taken with a full meal; no protein drink subsitution

Question 38

Efavirenz and food

Answer 38

take on a empty stomach at bedtime

Question 39

Boxed warning for all NNRTi

Answer 39

hepatotoxicity with severe rash

Question 40

Contraindication for rilpivirine

Answer 40

use with PPI (drug absorption is acid-dependent)

Question 41

Warning/side effect for rilpivirine

Answer 41

depression

insomnia

QT prolongation

Question 42

PI taken without food

Answer 42

fosamprevair oral solution

Question 43

Do NOT take Kaletra and ritonavir with __ __ or __

Answer 43

metronidazole

tinidazole

disulfram

Question 44

PI caution with sulfa allergy

Answer 44

darunavir

fosamprenavir

tipranavir

Question 45

fosamprenvir may cause ___ in patient’s with a sulfa allergy

Answer 45

hemolytic anemia

Question 46

CrCl cutoff for Stribild

Answer 46

<50; do not use

Question 47

CrCl cut off for Genvoya

Answer 47

<30; do not use

Question 48

Maraviroc only works with __ ___ disease.

Answer 48

CCR-5 tropic