History of Pharmacology

Question 1

What are three historical drugs that were used for medical reasons?

Answer 1

Cannabis, cocaine and opiods

Question 2

What is a pharmacopoeia?

Answer 2

First list of medicinal drugs

Question 3

Who compiled the first pharmacopoeia?

Answer 3

Dioscorides

Question 4

What are the first blockbuster drugs in the pharmaceutical industry?

Answer 4

Acetylsalicylic acid
Nitroglycerin
Morphine

Question 5

What was the key discovery of 1905?

Answer 5

Langley discovered that chemical mediators released by nerves and acted on ‘receptive substance’ (receptors)

Question 6

What was the key discovery of 1904?

Answer 6

Elliot discovered the concept of neurotransmission

Question 7

What was the Loewi experiment that built on neurotransmission?

Answer 7

Set up two frog hearts in close proximity, when the vagus nerve of the first heart and both hearts eventually slowed

Question 8

Which scientists discovered insulin and what was their experiment?

Answer 8

Banting and Best, took out dogs pancreas and treated them with secretions from the pancreas

Question 9

What is the sandwich experiment?

Answer 9

One aortic strip with endothelium was exposed to ACh and caused relaxation of the strip and caused the 2nd strip without an endothelium to relax as well

Question 10

How was penicillin discovered?

Answer 10

Mold growing on staphylococcus plate