History, Key Theorists And Key Pathogens Flashcards

1
Q

What historical figure is associated with the concept of spontaneous generation?

A

Aristotle

He proposed the idea of ‘pneuma’ or vital heat.

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2
Q

Who disproved spontaneous generation using swan-neck flasks?

A

Louis Pasteur

His work was pivotal in microbiology.

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3
Q

What is Koch’s postulate?

A

A framework to establish a causative relationship between a microbe and a disease.

It includes criteria such as the microbe being found in diseased organisms and not in healthy ones.

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4
Q

What significant discovery did Alexander Fleming make?

A

Isolated β-lactam from Penicillium chrysogenum in 1929

This led to the development of antibiotics to treat infections.

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5
Q

What was the role of Ignaz Semmelweis in microbiology?

A

Promoted handwashing to prevent puerperal fever.

His observations linked hygiene practices to patient outcomes.

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6
Q

What are Winogradsky columns used for?

A

To study microbial ecology in lab-based microcosms.

They help demonstrate relationships between microorganisms and their habitats.

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7
Q

Fill in the blank: The most common Gram-negative bacterium in the gastrointestinal tract is _______.

A

Escherichia coli

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8
Q

What is the main cause of tuberculosis?

A

Mycobacterium tuberculosis

It is transmitted via the airborne route.

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9
Q

What are the symptoms of tuberculosis?

A

Cough with bloody phlegm, loss of appetite, weight loss, fatigue, night sweats, fever

These symptoms can indicate a severe infection.

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10
Q

What is the treatment for influenza?

A

Standard care includes rest and paracetamol; Tamiflu in severe cases

Prevention strategies are also crucial.

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11
Q

True or False: Influenza virus is transferred from host via airborne droplets.

A

True

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12
Q

What is the role of probiotics in microbial ecology?

A

They are used therapeutically to benefit gut health.

Probiotics are live microorganisms that provide health benefits.

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13
Q

What is the global death toll from influenza annually?

A

290,000–650,000 deaths worldwide

This figure highlights the impact of influenza on public health.

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14
Q

What is the importance of handwashing in preventing Escherichia coli infections?

A

It helps prevent intestinal illnesses and nosocomial infections.

Proper hygiene practices are essential for infection control.

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15
Q

Fill in the blank: The BCG vaccine is used for the prevention of _______.

A

Tuberculosis

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16
Q

What are the main causes of staphylococcus aureus (MRSA)

A

Invades bloodstream to produce virulence factors

17
Q

How is Staphylococcus aureus (MRSA) detected

A

Via culture, nucleic acid tests, antibiotic susceptibility

18
Q

What are the symptoms of Staphylococcus aureus (MRSA)

A

Skin swelling, redness, infection
Which can then lead to bloodstream infections and pneumonia

19
Q

What are the symptoms of Staphylococcus aureus (MRSA)

A

Skin swelling, redness, infection
Which can then lead to bloodstream infections and pneumonia