History

Question 1

Miescher

Answer 1

Isolated Nuclein from pus
- first person to isolate
- began history of DNA

Question 2

Kossel

Answer 2

Isolated 5 bases and identified as nucleic acid
- name of DNA

Question 3

Levene

Answer 3

determined nucleic acids are made of po4, ribose (5c) sugar and N-base

Question 4

Koltsov

Answer 4

double helix model

Question 5

Griffith

Answer 5

Transforming Principle: chromosomes transmits info in bacteria/viruses

Question 6

Hammerling

Answer 6

Established nucleus as site of hereditary

Question 7

Avery, McCarty, MacLeod

Answer 7

DNA is probably the molecule of hereditary

Question 8

Chargaff

Answer 8

complementary bases are present in equal amounts

Question 9

Hershey & Chase

Answer 9

Confirmed DNA carries genetic info and not protein

Question 10

Pauling

Answer 10

Triple Helix Model (failed)

Question 11

Wilkins, Gosling & Franklin

Answer 11

suggested double helix shape after seeing x-ray diffraction photos

Question 12

Watson & Crick

Answer 12

Double helix model with sugar-phosphate backbone and bases paired on the inside as A-T and C-G