Historical figures in psychiatry Flashcards
Who reintroduced clozapine in to clinical practice?
Kane
Who developed the first SSRI (modified pheniramine to create zimelidine)?
Carlsson
Who first described the ‘cheese effect’ seen in MAOI use?
Blackwell
Who discovered lithium’s beneficial effect in mania?
Cade
Who discovered use of iproniazid (MAOI)?
Kline
Who synthesised chlorpromazine?
Charpentier
Who introduced chlorpromazine as a treatment for schizophrenia and coined the term ‘neuroleptic’?
Delay and Deniker
Who discovered the antidepressant effects of imipramine?
Kuhn
Who used ECT first?
Cerletti (and Bini)
Who coined the term ‘antidepressant’?
Lurie
Who discovered insulin shock therapy?
Sakel
Who developed frontal leucotomy for psychosis?
Moniz
Who developed metrazol therapy?
Meduna
What was the first antidepressant?
What was the first SSRI?
First antidepressant was the MOA iproniazid
Lurie coined the term ‘antidepressant’
Zimelidine was first SSRI (Carlsson, 1996) to be developed (in 1972)
Zimeldine marketed in Europe as the first SSRI in 1982
In 1988 Fluoxetine was launched to the US market under the trade name Prozac
What was Alfred Adler known for?
Believed that the main driving force in personality is a striving for superiority.
What was Carl Jung known for?
Introduced the concept of the persona (mask) which is the part of the ego presented to other people. The other (more hidden) part of the self is the ‘shadow’.
Differentiated between the personal unconscious (which contains an individual’s personal memories) and collective unconscious (a set of memories and ideas that is shared amongst all of humanity).
Talked of archetypes (symbolic images in the collective unconscious). Important archetypes are anima (female principle), animus (male principle), the shadow, and the self.
What was Erik Erickson known for?
Known for his stages of psychosocial development.
What was Harry Stack Sullivan known for?
Credited with the introduction of interpersonal therapy.
What was Wilfred Bion known for?
Theories on group dynamics
Saw each group as having a work group and a basic assumption group
Three basic assumptions, fight or flight, dependency, and pairing
What was John Bowlby known for?
Attachment theory.