HISTOPLASMA CAPSULATUM Flashcards

1
Q

Morfología del hongo histoplasma?

A
    • Forma infectante: Filamentoso con macro/microconidias

2. - Forma patogena: levadura (pared delgada, ovalado y uninucleo)

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2
Q

Forma de transmisión de la histoplasmosis?

A

Inhalación de externa de murciélagos y aves

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3
Q

Nombres alternativos de la histoplasmosis?

A

Enfermedad de Darling, cavernas,VALLE DE OHIO, y reticuloendoteliosi

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4
Q

Factores de riesgo para histoplasmosis?

A

Riesgo ocupacional e inmunodeficiencia

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5
Q

Forma clinica mas frecuente de histoplasmosis?

A

En 95% casos es asintomática, subclinica o benigna

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6
Q

Periodo de incubación de histoplasmosis?

A

5 a 18 dias

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7
Q

Clinica de histoplasmosis cavilaría pulmonar cronica?

A

Anciano con EPOC y: perdida ponderal, fatiga, fiebre, tos con esputo purulento y hemoptisis

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8
Q

Órganos que afecta la histoplasmosis diseminada?

A

Pulmón difuso, Suprarrenales, SNC, piel, medula osea, hígado y bazo

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10
Q

Complicaciones de histoplasmosis pulmonar?

A

Rotura ganglios inlfamados, mediastinitis (granulomatosa, fibrosa), pericarditis

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13
Q

Radiografía en histoplasmosis?

A

Infiltrados reticulonodulares y adenpatia biliar o mediastinal

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15
Q

Diagnóstico definitivo de histoplasmosis?

A

Cultivo (6 semanas)

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16
Q

Métodos alternativos diagnosticos de histoplasmosis?

A
  • Biopsias con tincion PAS o metenamia argentica

- Serología +

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17
Q

Tratamiento para histoplasmosis leve y moderada?

A

1a linea: IRACONAZOL

2a linea: Fluco y ketoconazol

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18
Q

Tratamiento para histoplasmosis grave y mortal?

A

Eleccion: Anfotericina B

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19
Q

Cuando se beneficia del uso de metilprednisolona en histoplasmosis?

A

Si dificultad respiratoria

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