Histopathology (All Topics) Flashcards
Cardiac Pathology:
What is the definition of atherosclerosis?
Cardiac Pathology:
What are the steps in atherogenesis?
Cardiac Pathology:
What are the 3 principal components of atherosclerotic plaques?
Cardiac Pathology:
Which blood vessels are more commonly affected?
How are they affected?
Cardiac Pathology:
What are the modifiable and non-modifiable risk factors for atherosclerosis?
Myocardial Infarction:
What is the pathogenesis of Myocardial Infarction?
Myocardial Infarction:
What are the mechanical complications of Myocardial Infarction?
Myocardial Infarction:
What are the arrhythmia caused by Myocardial Infarction?
Myocardial Infarction:
What are the pericardial complications of Myocardial Infarction?
Myocardial Infarction:
What is the evolution of Myocardial Infarction Histological findings?
Heart failure:
What are the common causes of Heart Failure?
Heart failure:
What are the complications of Heart Failure?
Heart failure:
What is the pathophysiology of Heart Failure?
Heart failure:
What does left Ventricular Failure cause?
Heart failure:
What does Right Ventricular Failure cause?
Heart failure:
What is the definition, common phenotype and histological findings of Hypertrophic Cardiomyopathy?
Heart failure:
What are the genetic defects in Hypertrophic Cardiomyopathy?
Heart failure:
What effect can Hypertrophic Cardiomyopathy in young people?
What is Hypertrophic Obstructive Cardiomyopathy and what are its effects?
Cardiomyopathy:
What is/are the mechanism, causes and indirect myocardial dysfunction of Dilated cardiomyopathy?
Cardiomyopathy:
What is/are the mechanism, causes and indirect myocardial dysfunction of Hypertrophic cardiomyopathy?
Cardiomyopathy:
What is/are the mechanism, causes and indirect myocardial dysfunction of Restrictive cardiomyopathy?
Myocardial Infarction:
What is a Mural Thrombus?
Cardiomyopathy
What is Arrythmogenic Right Ventricular Cardiomyopathy (ARVC)?
Acute Rheumatic Fever:
What is the peak age of Rheumatic Fever?
What are its effects on:
- Heart
- Joints
- Skin
- CNS
Acute Rheumatic Fever:
What are the major clinical features of Acute Rheumatic Fever?
What is the Jones Major Criteria?
Acute Rheumatic Fever:
What are the minor symptoms of Acute Rheumatic Fever?
Acute Rheumatic Fever:
What are the common causative organisms?
Acute Rheumatic Fever:
What is the treatment of Acute Rheumatic Fever?
Infective Endocarditis:
What are the causes of Infective Endocarditis?
Infective Endocarditis:
What are the causative organisms, virulence, vegetation morphology and spread of Acute and Subacute Infective Endocarditis?
Infective Endocarditis:
What are the clinical features of Infective Endocarditis?
Infective Endocarditis:
What values are commonly affected in Infective Endocarditis?
Infective Endocarditis:
What is the Duke criteria?
Infective Endocarditis:
What what is the treatment of Infective Endocarditis?
Infective Endocarditis:
What is Chronic Rheumatic valve disease?
Infective Endocarditis:
What is Mitral valve prolapse?
Vegetative Endocarditis:
What is/are the pathology and characteristics of Vegetations of Rheumatic heart disease?
Vegetative Endocarditis:
What is/are the pathology and characteristics of Vegetations of Infective endocarditis?
Vegetative Endocarditis:
What is/are the pathology and characteristics of Vegetations of Non-bacterial thrombotic endocarditis (marantic)?
Vegetative Endocarditis:
What is/are the pathology and characteristics of Vegetations of Libman-Sacks endocarditis?
Valve disease:
What is/are the pathophysiology and causes of Aortic Stenosis?
Valve disease:
What is/are the pathophysiology and causes of Aortic Regurgitation?
Valve disease:
What is/are the pathophysiology and causes of Mitral Stenosis?
Valve disease:
What is/are the pathophysiology and causes of Mitral Regurgitation?
Pericarditis:
What is the definition of Pericarditis and what are the subtypes?
Pericarditis:
What is the definition of Pericardial effusion and Hemopericardium?
Oesophagus:
What are the tissues lining the Oesophagus?
Oesophagus:
What are the main Paediatric Congenital Gastrointestinal Diseases?
Oesophagus:
What is/are aetiology, symptoms, genetics, investigations and treatment for hirschsprung’s disease?
Oesophagus:
What are the Mechanical Acquired Gastrointestinal diseases?
Oesophagus:
What are the inflammatory Acquired Gastrointestinal diseases?
Oesophagus:
What are the ischaemic Acquired Gastrointestinal diseases?
Oesophagus:
What are the characteristics of reflux oesophagitis (GORD)?
- Complications
- Treatment
Oesophagus:
What are the characteristics of Barrett’s oesophagus?
Oesophagus:
What are the characteristics of Oesophageal Adenocarcinoma?
Oesophagus:
What are the characteristics of Squamous cell oesophageal carcinoma?
- Aetiology
- Epidemiology
Oesophagus:
What are the characteristics of Squamous cell oesophageal carcinoma?
- Presentation.
Oesophagus:
What are the characteristics of Varices?
Stomach:
What are the cells lining the stomach?
Stomach:
What are the characteristics of Gastritis, Acute and Chronic?
Stomach:
What are the characteristics for the special types of Gastritis?
Stomach:
What are the characteristics of Gastric ulcer?
- Symptoms
Stomach:
What are the characteristics of Gastric ulcer?
- Risk factors
- Investigations
- Complications
Stomach:
What are the characteristics of Gastric lymphoma?
Duodenum:
What are the characteristics of Duodenal ulcer?
Duodenum:
What are the characteristics of Coeliac disease?
- Aetiology
- Symptoms
Duodenum:
What are the characteristics of Coeliac disease?
- Investigation
- Management
Acquired Diseases:
What is the epidemiology for Crohn’s Disease?
Acquired Diseases:
What is the aetiology for Crohn’s Disease?
Acquired Diseases:
What is the pathophysiology for Crohn’s Disease?
Acquired Diseases:
What are the Clinical features of Crohn’s Disease?
Acquired Diseases:
What are the complications of Crohn’s Disease?
Acquired Diseases:
What are the investigations for Crohn’s Disease?
Acquired Diseases:
What is the management for Crohn’s Disease?
Acquired Diseases:
What is the epidemiology for Ulcerative Colitis?
Acquired Diseases:
What is the aetiology for Ulcerative Colitis?
Acquired Diseases:
What is the pathophysiology for Ulcerative Colitis?
Acquired Diseases:
What are the clinical features of Ulcerative Colitis?
Acquired Diseases:
What are the extra-GI manifestations of Ulcerative Colitis and Crohn’s disease?
Acquired Diseases:
What are the complications of Ulcerative Colitis?
Acquired Diseases:
How do you investigate Ulcerative Colitis?
Acquired Diseases:
How do you manage Ulcerative Colitis?
Oesophagus:
What is the classification of Acquired Gastrointestinal Diseases?
-
Mechanical
- Obstruction
-
Inflammatory
- Acute colitis
- Chronic Colitis
-
Ischaemia
- Ischaemic coclitis
Tumours of the colon and rectum:
How are tumours of the colon and rectum classified?
-
Neoplastic Polyps
- Adenomas
-
Non-Neoplastic polyps
- Hamartomatous polyp
- Hyperplastic polyp
- Inflammatory
- Colorectal cancer
Tumours of the colon and rectum:
What is/are the definition, aetiology epidemiology and classification of Adenomas Neoplastic Polyps?
Tumours of the colon and rectum:
What are is/are the disease progression and risk factors for malignancy of Adenomas Neoplastic Polyps?
Tumours of the colon and rectum:
What is/are the genetics and epidemiology of Hamartomatous polyps?
Tumours of the colon and rectum:
What disease are Hamartomatous polyps also seen in and what do they carry an increased risk of?
Tumours of the colon and rectum:
What are the clinical feature of Hyperplastic Syndrome?
Tumours of the colon and rectum:
What are the clinical features of Inflammatory Syndrome?
Tumours of the colon and rectum:
What is the epidemiology of colorectal cancer?
Tumours of the colon and rectum:
What is the aetiology of colorectal cancer?
Tumours of the colon and rectum:
What are the clinical features of colorectal cancer?
Tumours of the colon and rectum:
What are the investigations of colorectal cancer?
Tumours of the colon and rectum:
What is the classification of colorectal cancer?
Tumours of the colon and rectum:
What is the management of colorectal cancer?
Tumours of the colon and rectum:
What are the features of Familial adenomatous polyposis (FAP)?
Tumours of the colon and rectum:
What are the features of Hereditary nonpolyposis colorectal cancer/Lynch syndrome (HNPCC)?
Tumours of the colon and rectum:
What is/are the aetiology, investigations and management of C.Difficile?
Tumours of the colon and rectum:
What is/are the aetiology, symptoms and complications of diverticular disease?
Tumours of the colon and rectum:
What is the definition of Carcinoid Syndrome?
Tumours of the colon and rectum:
What are the differences between Carcinoid syndrome and Carcinoid crisis?
Tumours of the colon and rectum:
What are the investigations and management of Carcinoid Syndrome?
Tumours of the colon and rectum:
What are the familial syndromes of colorectal cancer?
- Familial adenomatous polyposis (FAP)
- Hereditary non-polyposis colorectal cancer/L
Pancreatic Disease:
What are the functions, secretions and islets of Langerhans for Exocrine glands?
Pancreatic Disease:
What are the functions, secretions and islets of Langerhans for Endocrine glands?
Pancreas:
What is the role of the pancreas?
What is secretin? (add and buffering with HCO3-)
Pancreas:
What is CCK?
Pancreas:
What is/are the aetiology, symptoms and signs of Metabolic Syndrome?
Pancreas:
How is Diabetes Mellitus Diagnosed?
Pancreas:
What is T1DM and T2DM?
Pancreas:
What are the complications of Diabetes?
Pancreas:
What is/are the aetiology, presentation and histology of acute pancreatitis?
Pancreas:
What is/are the aetiology, presentation, histology and complications of chronic pancreatitis?
Pancreas:
What is/are the aetiology, presentation, histology and prognosis of Acinar Cell Carcinoma?
Neuroendocrine Tumours:
What is/are the aetiology and genetics of Neuroendocrine tumours?
Neuroendocrine Tumours:
What are the functional and nonfunctional Neuroendocrine tumours?
Neuroendocrine Tumours:
What are the investigations and management of Neuroendocrine tumours?
Neuroendocrine Tumours:
What is the aetiology of Multiple Endocrine Neoplasia?
Neuroendocrine Tumours:
What are the main Pancreatic Malformations?
Pancreatic Carcinoma:
What are the epidemiology, site and risk factors of ductal adenocarcinoma of the pancreas?
Pancreatic Carcinoma:
What are the clinical features of ductal adenocarcinoma of the pancreas?
Pancreatic Carcinoma:
How do you investigate adenocarcinoma of the pancreas?
Pancreatic Carcinoma:
How do you manage adenocarcinoma of the pancreas?
Liver Pathology:
What is the basic structure of the Liver?
Liver Pathology:
What are centrilobular and Periportal hepatocytes?
Liver Pathology:
What are the main functions of the liver?
Liver Pathology:
What is/are the definition and main features of Cirrhosis?
Liver Pathology:
What are the main causes of Cirrhosis?
Liver Pathology:
How can Cirrhosis be classified?
Liver Pathology:
What is the pathophysiology of Macronodular Cirrhosis?
Liver Pathology:
What are the implications of different Child Pugh scores?
Liver Pathology:
What is the definition of Portal Hypertension?
Liver Pathology:
What are the causes of Portal Hypertension?
Liver Pathology:
What is/are the definition and subtypes of Non Alcoholic Fatty Liver disease?
Liver Pathology:
What is/are the epidemiology, genetics, subtypes and treatment of Autoimmune Hepatitis?
Liver Pathology:
What is/are the definition, epidemiology, and investigations of Primary Biliary Cirrhosis (PBC)?
Liver Pathology:
What is/ are the histology, symptoms and treatment of Primary Biliary Cirrhosis (PBC)?
Liver Pathology:
What is/are the definition and epidemiology of Primary Sclerosing Cholangitis (PSC)?
Liver Pathology:
What are the investigations for Primary Sclerosing Cholangitis (PSC)?
Liver Tumours:
What are the clinical features of Hepatic adenoma?
Liver Tumours:
What are the clinical features of Haemangioma?
Liver Tumours:
What are the clinical features of Hepatocellular Carcinoma?
Liver Tumours:
What are the clinical features of Cholangiocarcinoma?
Liver Tumours:
What are the clinical features of Metastases from other primary tumours?
Modified Child Pugh Score:
What is the score of 1, score of 2 and score of 3 for:
- Ascites
- Encephalopathy
- Bilirubin
- Albumin
- Prothrombin time (sec > normal).
Alcoholic Liver Disease:
What are the macroscopic and microscopic characteristics of Hepatic Steatosis (Fatty Liver)?
Alcoholic Liver Disease:
What are the macroscopic and microscopic characteristics of Alcoholic hepatitis?
Alcoholic Liver Disease:
What are the macroscopic and microscopic characteristics of Alcoholic Cirrhosis?
Genetic Causes of Cirrhosis:
What is the incidence, age, pathophysiology and histology of Haemochromatosis?
Genetic Causes of Cirrhosis:
What are the signs/symptoms and investigations of Haemochromatosis?
Genetic Causes of Cirrhosis:
What is the incidence, age, pathophysiology and histology of Wilson’s Disease?
Genetic Causes of Cirrhosis:
What are the signs/symptoms and investigations of Wilson’s Disease?
Genetic Causes of Cirrhosis:
What is the incidence, age, pathophysiology and histology of Alpha 1 Antitrypsin Deficiency?
Genetic Causes of Cirrhosis:
What are the signs/symptoms and investigations of Alpha 1 Antitrypsin Deficiency?
Liver Pathology:
What happens when portal pressure exceeds 10 to 12 mmHg?
Liver Pathology: What are the causes of Cirrhosis?
Alcoholic hepatitis Hepatic steatosis Alcoholic Cirrhosis Non Alcoholic Fatty Liver Disease Viral Hepatitis Autoimmune hepatitis Biliary causes of cirrhosis Primary biliary cirrhosis Primary Sclerosing cholangitis
Liver Tumours:
What is the classification of liver tumours?
-
Benign
- Hepatic adenoma
- Haemangioma
-
Malignant
- Hepatocellular
- Carcinoma
- Angiosarcoma
- Hepatoblastoma
- Cholangiosarcoma
- Metastasis from other primary sources
Urological Pathology:
What is/are the subtypes and aetiology of Cystitis?
Urological Pathology:
What are the predisposing factors and clinical features of Cystitis?
Urological Pathology:
What are the complications and treatment of Cystitis?
Urological Pathology:
What are the main types of Bladder tumours?
- Transitional cell tumours
- Squamous cell carinoma
- Adenocarinoma
Urological Pathology:
What is/are the epidemiology and contributing factors of Transitional Cell tumours?
Urological Pathology:
What is/are the clinical features and diagnosis of Transitional Cell tumours of the bladder Bladder?
Urological Pathology:
What are the features of Squamous cell carinoma Bladder tumours?
Urological Pathology:
What are the features of Adenocarcinoma Bladder tumours?
Urological Pathology:
What is/are the aetiology, symptoms and treatment of Benign Prostatic Hyperplasia (BPH)?
Urological Pathology:
What is/are the aetiology, risk factor, grading and diagnosis of Prostate Cancer?
Urological Pathology:
What are the subtypes of Prostitis and their causes?
Urological Pathology:
What are the features of Seminoma testicular tumours?
Urological Pathology:
What are the features of Teratoma testicular tumours?
Urological Pathology:
What are the features of Maldescent of testis?
Testicular Tumours:
What are the % incidence, types and predisposing factors for Germ cell testicular tumours?
Testicular Tumours:
What are the % incidence, types and predisposing factors for sex chord - stromal testicular tumours?
Urological Pathology:
What are the types of testicular tumours?
- Seminoma
- Teratoma
- Maldescent of testis
Renal pathology:
How can diseases of the kidney be classified?
Renal pathology:
What is Nephrotic Syndrome and what are the key words in EMQs for it?
Renal pathology:
What is Nephritic syndrome and the symptoms it presents with?
Renal pathology:
What are the symptoms of Acute Postinfectious Glomerulonephritis?
Renal pathology:
What is/are investigations and Biopsy findings of Acute Postinfectious Glomerulonephritis?