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Year 5 Alex's Path total > Haematology (All Topics) > Flashcards

Haematology (All Topics) Flashcards

1
Q

Anaemia:

What is the definition of anaemia and what are its causes?

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2
Q

Anaemia:

What are the symptoms and signs of anaemia?

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3
Q

Microcytic Anaemia:

Outline the signs, blood film findings and causes of IDA

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4
Q

Microcytic Anaemia:

What are the causes of Iron Deficiency Anaemia?

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5
Q

Microcytic Anaemia:

What is the treatment of Iron Deficiency Anaemia?

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6
Q

Macrocytic Anaemia:

What is are the sources of Vitamin B12 and what are the causes of its deficiency?

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7
Q

Macrocytic Anaemia:

What are the clinical features of Vitamin B12?

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8
Q

Macrocytic Anaemia:

What is Pernicious anaemia?

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9
Q

Macrocytic Anaemia:

What is the treatment of Vitamin B12 Deficiency?

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10
Q

Macrocytic Anaemia:

What are the sources of Folate?

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11
Q

Macrocytic Anaemia:

What are the causes of Folate deficiency?

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12
Q

Macrocytic Anaemia:

What is the treatment of Folate deficiency?

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13
Q

Anaemia:

What are the causes of Microcytic, Normocytic and Macrocytic Anaemia?

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14
Q

Micro/Normocytic Anaemia:

What is the pathogenesis of Renal Failure driven Anaemia of Chronic Disease?

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15
Q

Micro/Normocytic Anaemia:

What is/are the definition of and causes of Anaemia of Chronic Disease?

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16
Q

Micro/Normocytic Anaemia:

How are ferritin levels affected in Anaemia of Chronic Disease?

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17
Q

Normocytic Anaemia:

What are the inflammatory markers of Chronic Disease?

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18
Q

Microcytic Anaemia:

What is the definition and diagnosis of Sideroblastic Anaemia?

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19
Q

Microcytic Anaemia:

What are the causes and treatment options for Sideroblastic Anaemia?

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20
Q

Haemolytic Anaemias:

What is the definition of haemolytic anaemia?

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21
Q

Haemolytic Anaemias:

What are the features of all, intravascular and extravascular haemolytic anaemias?

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22
Q

Haemolytic Anaemias:

What are the causes of inherited and acquired anaemia?

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23
Q

Haemolytic Anaemias:

What are the features of hereditary spherocytosis?

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24
Q

Haemolytic Anaemias:

What are the features of Hereditary elliptocytosis?

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25
**_Haemolytic Anaemias:_** What are the features of Southeast asian Ovalocytosis?
26
**_Haemolytic Anaemias:_** What is the inheritance, epidemiology of G6PD deficiency and what are the features of its attacks?
27
**_Haemolytic Anaemias:_** What are the investigations and management of G6PD deficiency?
28
**_Haemolytic Anaemias:_** What are the features of pyruvate kinase deficiency?
29
**_Sickle Cell Anaemia:_** What are the important features of Haemolysis and Vaso Occlusion in Sickle cell anaemia?
30
**_Sickle Cell Anaemia:_** What are the typical symptoms in Children, teens and Adults with Sickle cell anaemia?
31
**_Sickle Cell Anaemia_** What are the rarer subtypes of Sickle Cell Anaemia?
32
**_Sickle Cell Anaemia_** Outline the typical initial presentations of sickle cell anaemia How do Sick cells change in low Oxygen?
33
**_Sickle Cell Anaemia:_** Outline the genetics and main subtypes of Sickle Cell Anaemia
34
**_Sickle Cell Anaemia:_** What are the investigations and management of sickle cell anaemia?
35
**_Haemoglobinopathies:_** What is the definition of thalassaemia?
36
**_Haemoglobinopathies:_** What is/are the genetics and presentation of Beta Thalassaemia?
37
**_Haemoglobinopathies:_** What are the subtypes of Beta Thalassaemia?
38
**_Haemoglobinopathies:_** What is the diagnosis and treatment of Thalassaemia?
39
**_Haemoglobinopathies:_** What are the features of Alpha Thalassaemia?
40
**_Acquired Haemolytic Autoimmune Anaemias:_** What are the features of Warm and Cold autoimmune haemolytic anaemia?
41
**_Acquired Haemolytic Autoimmune Anaemias:_** What are the causes of Warm and Cold autoimmune haemolytic anaemia?
42
**_Acquired Haemolytic Autoimmune Anaemias:_** What is the management of Warm and Cold autoimmune haemolytic anaemia?
43
**_Acquired Haemolytic Autoimmune Anaemias:_** What are the features of Paroxysmal cold haemoglobinuria (PCH)?
44
**_Acquired Non–Immune Haemolytic Anaemias:_** What is/are the aetiology and symptoms of Paroxysmal nocturnal haemoglobinuria?
45
**_Acquired Non–Immune Haemolytic Anaemias:_** What is/are the investigations and management of Paroxysmal nocturnal haemoglobinuria?
46
**_Acquired Non–Immune Haemolytic Anaemias:_** What is/are the aetiology and causes of Microangiopathic Haemolytic Anaemia (MAHA)?
47
**_Acquired Non–Immune Haemolytic Anaemias:_** What is/are the aetiology and causes of Thrombotic thrombocytopenia purport?
48
**_Acquired Non–Immune Haemolytic Anaemias:_** What is/are the aetiology and causes of Haemolytic Uraemic Syndrome?
49
**_Acquired Haemolytic Autoimmune Anaemias:_** What are the types of autoimmune acquired haemolytic anaemia?
1. _Autoimmune_ 1. Warm Autoimmune Haemolytic Anaemia 2. Cold Agglutinin Disease 3. Paroxysmal cold haemoglobinuria 2. _Nonimmune Paroxysmal nocturnal haemoglobinuria_ 1. Microangiopathic Haemolytic Anaemia 2. Thrombocytopenic Purpura 3. Haemolytic Uraemic syndrome
50
**_Haemostasis_** Outline the main processes in forming a stable Haemostatic plug
51
**_Haemostasis_** Outline the main steps of the Coagulation cascade
52
**_Blood tests for Coagulation disorders:_** Outline the results for INR, APTT, Thrombin time, Platelet count and Bleeding time for: 1. Heparin 2. DIC 3. Liver Disease 4. Platelet defect 5. Vit K Deficiency 6. Haemophilia 7. vWF Disease
53
**_Venous Thrombosis_** Outline the main risk factors for and causes of Venous Thromboembolism (VTE)
54
**_Haemostasis:_** What are the phases of haemostasis?
55
**_Haemostasis:_** What are the key inhibitors of haemostasis?
56
**_Haemostasis:_** What does the Activated partial thromboplastin (APTT) measurement track?
57
**_Haemostasis:_** What does the Prothrombin time (PT) measurement track?
58
**_Haemostasis:_** What does the Thrombin time (TT) measurement track?
59
**_Bleeding disorders:_** What are the causes of bleeding disorders and what are the features of Vascular and Coagulation disorders?
60
**_Bleeding disorders:_** What are the main vascular defect bleeding disorders?
61
**_Bleeding disorders:_** What are the main causes of platelet disorders?
62
**_Bleeding disorders:_** What is/are the peak age, F:M ratio, preceding infection, onset of symptoms, platelet count, duration and spontaneous remission of Acute ITP and Chronic ITP?
63
**_Bleeding disorders:_** What is/are the epidemiology, genetics and presentation of Haemophilia A?
64
**_Bleeding disorders:_** What is/are the investigations and management of Haemophilia A?
65
**_Bleeding disorders:_** What are the features of Haemophilia B?
66
**_Bleeding disorders:_** What is/are the subclasses and genetics of Von Willebrand’s disease?
67
**_Bleeding disorders:_** What is/are the presentation, diagnosis and management of Von Willebrand’s disease?
68
**_Bleeding disorders:_** Acquired coagulation disorders: What is/are the aetiology, investigations and management of Disseminated intravascular coagulation (DIC)?
69
**_Bleeding disorders:_** Acquired coagulation disorders: What are the effects of liver disease on coagulation?
70
**_Bleeding disorders:_** Acquired coagulation disorders: What is/are the aetiology and treatment of Vitamin K Deficiency on coagulation?
71
**_Bleeding disorders:_** Outline the prophylactic treatment of VTE
72
**_Bleeding disorders:_** Outline the treatment of DVT/PE
73
**_Bleeding disorders:_** What is the mechanism of action of Heparin? What is its antidote?
74
**_Bleeding disorders:_** What is the mechanism of action of Warfarin? What is its antidote?
75
**_Bleeding disorders:_** What are the indications for target INRs of 2.5 and 3.5?
76
**_Bleeding disorders:_** What is the protocol for INR levels of: 1. 5 to 8, no bleeding 2. 5 to 8 bleeding 3. \>8 no bleeding/minor bleed 4. Major bleeding (including intracranial haemorrhage)
77
**_Leukaemia:_** What is/are the definition of and clinical features of Acute Leukaemia?
78
**_Leukaemia:_** What is the aetiology of Acute Leukaemia?
79
**_Leukaemia:_** What are the investigations for Acute Leukaemia?
80
**_Leukaemia:_** What is/are the epidemiology and clinical features of Acute Lymphoblastic Leukaemia and Acute Myeloid Leukaemia?
81
**_Leukaemia:_** What are the investigations for Acute Lymphoblastic Leukaemia and Acute Myeloid Leukaemia?
82
**_Leukaemia:_** What is the treatment for Acute Lymphoblastic Leukaemia and Acute Myeloid Leukaemia?
83
**_Leukaemia:_** What is/are the aetiology, epidemiology and clinical features of Chronic Myeloid Leukaemia?
84
**_Leukaemia:_** What are the investigations for Chronic Myeloid Leukaemia?
85
**_Leukaemia:_** What are the phases of Chronic Myeloid Leukaemia?
86
**_Leukaemia:_** What is/are the aetiology and epidemiology of Chronic Lymphocytic Leukaemia?
87
**_Leukaemia:_** What are the investigations for Chronic Lymphocytic Leukaemia?
88
**_Leukaemia:_** What are the prognostic factors for Chronic Lymphocytic Leukaemia?
1
89
**_Leukaemia:_** What the staging for factors for Chronic Lymphocytic Leukaemia?
90
**_Leukaemia:_** What is the treatment for Chronic Lymphocytic Leukaemia?
91
**_Leukaemia:_** What are the clinical feaures of Chronic Lymphocytic Leukaemia?
92
**_Lymphoma_** What are the subtypes of Lymphoma?
* **_Hodgekin's_** * **_Non-Hodgekin's_** * **T Cell Lymphoma** * Anaplastic large cell lymphoma * Peripheral T-Cell Lymphoma * Adult T cell leukaemia/lymphoma * Enteropathy-associated T cell lymphoma (EATL) * Cutaneous T Cell Lymphoma * **B-Cell Lymphoma** * Burkitt’s * Diffuse Large B-cell (DLBC) * Mantle cell lymphoma * Follicular * Mucosal associated lymphoid tissue (MALT)
93
**_Hodgkin's Lymphoma:_** What is/are the epidemiology and clinical presentation of Hodgkin’s Lymphoma?
94
**_Hodgkin's Lymphoma:_** What are the investigations of Hodgkin’s Lymphoma?
95
**_Hodgkin's Lymphoma:_** What is the treatment for Hodgkin’s Lymphoma?
96
**_Hodgkin's Lymphoma:_** What is the staging for Hodgkin’s Lymphoma?
97
**_Stem Cell Transplants:_** What are stem cell/bone marrow transplants? Which diseases are they used in?
98
**_Stem Cell Transplants:_** What are the features of Autologous SCT?
99
**_Stem Cell Transplants:_** What are the features of Allogeneic SCT?
100
**_Non–Hodgkin's Lymphoma:_** What is the classification of Non–Hodgkin's Lymphoma?
101
**_Non–Hodgkin's Lymphoma:_** What are the similarities in the clinical presentations of Non–Hodgkin's Lymphoma?
102
**_Non–Hodgkin's Lymphoma:_** How is Non–Hodgkin's Lymphoma staged?
103
**_Non–Hodgkin's Lymphoma:_** What are the features of Anaplastic Large Cell Lymphoma?
104
**_Non–Hodgkin's Lymphoma:_** What are the features of Peripheral T Cell Lymphoma?
105
**_Non–Hodgkin's Lymphoma:_** What are the features of Adult T Cell Lymphoma?
106
**_Non–Hodgkin's Lymphoma:_** What are the features of Enteropathy Associated Leukaemia/Lymphoma (EATL)?
107
**_Non–Hodgkin's Lymphoma:_** What are the features of Cutaneous T Cell Lymphoma?
108
**_B Cell Lymphoma:_** What are the features, histology and treatment of Burkitt’s Lymphoma?
109
**_B Cell Lymphoma:_** What are the features, histology and treatment of Burkitt’s Lymphoma (Endemic)?
110
**_B Cell Lymphoma:_** What are the features, histology and treatment of Burkitt’s Lymphoma (Sporadic)?
111
**_B Cell Lymphoma:_** What are the features, histology and treatment of Burkitt’s Lymphoma (Immunodeficiency)?
112
**_B Cell Lymphoma:_** What are the features, histology and treatment of Diffuse Large B Cell Lymphoma (DLBCL)?
113
**_B Cell Lymphoma:_** What are the features, histology and treatment of Mantle Cell Lymphoma?
114
**_B Cell Lymphoma:_** What are the features, histology and treatment of Follicular Lymphoma?
115
**_B Cell Lymphoma:_** What are the features, histology and treatment of Mucosal associated Lymphoid Tissue (MALT)?
116
**_Multiple Myeloma:_** What is the aetiology of Multiple Myeloma?
117
**_Multiple Myeloma:_** What is/are the investigations and staging for Multiple Myeloma?
118
**_Multiple Myeloma:_** What is the treatment of Multiple Myeloma?
119
**_Multiple Myeloma:_** What is/are the the aetiology, epidemiology, symptoms and treatment of Waldrendroms Macroglobulinemia?
120
**_Multiple Myeloma:_** What is/are the the aetiology, symptoms, investigations and treatment of Systemic Amyloidosis?
121
**_Lymphoma_** Outline the definition of Lumphoma and the areas that it can manifest
122
**_Multiple Myeloma_** Outline the M Spike, Bone Marrow findings, CRAB, Organ damage and Sigificance of: 1. MGUS 2. Smouldering MM 3. Multiple Myeloma
123
**_Blood transfusions:_** When is it necessary to transfuse Red Blood Cells?
124
**_Blood transfusions:_** When is it necessary to transfuse platelets?
125
**_Blood transfusions:_** When is it necessary to transfuse Fresh Frozen Plasma?
126
**_Haemodynamic disease of the Newborn:_** What is Haemodynamic disease of the newborn?
127
**_Haemodynamic disease of the Newborn:_** How is Anti D formation prevented in pregnancy?
128
**_Transfusion reactions:_** What are the immediate and delayed immune adverse reaction?
129
**_Transfusion reactions:_** What are the immediate and delayed non-immune adverse reaction?
130
**_Transfusion Reaction Flowchart_** Outline the transfusion reaction flowchart
131
**_Peripheral Blood Films:_** Outline the appearance, description of and underlying conditions of Acanthocytes
132
**_Peripheral Blood Films:_** Outline the appearance, description of and underlying conditions of Basophilic RBC stippling
133
**_Peripheral Blood Films:_** Outline the appearance, description of and underlying conditions of Burr Cells
134
**_Peripheral Blood Films:_** Outline the appearance, description of and underlying conditions of Heinz Bodies
135
**_Peripheral Blood Films:_** Outline the appearance, description of and underlying conditions of Howel-Jolly Bodies
136
**_Peripheral Blood Films:_** Outline the appearance, description of and underlying conditions of Leucoerythroblastic Anaemia
137
**_Peripheral Blood Films:_** Outline the appearance, description of and underlying conditions of Pelger Huet Cells
138
**_Peripheral Blood Films:_** Outline the appearance, description of and underlying conditions of Polychromasia
139
**_Peripheral Blood Films:_** Outline the appearance, description of and underlying conditions of Reticulocytosis
1
140
**_Peripheral Blood Films:_** Outline the appearance, description of and underlying conditions of Right Shift
141
**_Peripheral Blood Films:_** Outline the appearance, description of and underlying conditions of Rouleaux formation
142
**_Peripheral Blood Films:_** Outline the appearance, description of and underlying conditions of Schistocytes
143
**_Peripheral Blood Films:_** Outline the appearance, description of and underlying conditions of Spherocytes
144
**_Peripheral Blood Films:_** Outline the appearance, description of and underlying conditions of Stomatocytes
145
**_Peripheral Blood Films:_** Outline the appearance, description of and underlying conditions of Target Cells
146
**_Myeloproliferative Disorders:_** What is/are the definition of Myeloproliferative Disorder?
147
**_Myeloproliferative Disorders:_** What is the definition and sub-classification of Polycythaemia?
148
**_Myeloproliferative Disorders:_** What is the definition of Relative Polycythaemia?
149
**_Myeloproliferative Disorders:_** What is the definition of Polycythaemia Rubra Vera (PRV)?
150
**_Myeloproliferative Disorders:_** What are the the investigations for Polycythaemia Rubra Vera (PRV)?
151
**_Myeloproliferative Disorders:_** What is the treatment for Polycythaemia Rubra Vera (PRV)?
152
**_Myelofibrosis:_** What is the definition of Myelofibrosis?
153
**_Myelofibrosis:_** What are the investigations for Myelofibrosis?
154
**_Myelofibrosis:_** What is the treatment for Myelofibrosis?
155
**_Essential Thrombocythemia:_** What is the definition of Essential Thrombocythemia?
156
**_Essential Thrombocythemia:_** What are the investigations for Essential Thrombocythemia?
157
**_Essential Thrombocythemia:_** What is the treatment for Essential Thrombocythemia?
158
**_Myeloproliferative Disorders:_** What is sub-classification of Myeloproliferative Disorder?
159
**_Myeloproliferative Disorders:_** What mutations are common in Philadelphia negative Myeloproliferative Disorder? What is Myeloproliferative Disorder associated with?
160
**_Myeloproliferative Disorders:_** What are the clinical features of Polycythaemia Rubra Vera (PRV)?
161
**_Essential Thrombocythemia:_** Whatare the clincal features of Essential Thrombocythemia?
162
**_Myelofibrosis:_** What are the clinical features of Myelofibrosis?
163
**_Myelodysplastic syndromes:_** What is/are the definition of and characterising factors of Myelodysplastic Syndromes?
164
**_Myelodysplastic syndromes:_** What is the emipdemiology and definition of Myelodysplastic Syndromes?
165
**_Myelodysplastic syndromes:_** What is the treatment of Myelodysplastic Syndromes?
166
**_Myelodysplastic syndromes:_** What is the prognosis of Myelodysplastic Syndromes?
167
**_Myelodysplastic syndromes:_** What is are the blood features and bone marrow features of Refractory Anaemia (RA)?
168
**_Myelodysplastic syndromes:_** What is are the blood features and bone marrow features of Refractory Anaemia with ringed sideroblasts (RA+RA)?
169
**_Myelodysplastic syndromes:_** What is are the blood features and bone marrow features of Refractory cytopenia multilineage dysplasia (RCMD)?
170
**_Myelodysplastic syndromes:_** What is are the blood features and bone marrow features of Refractory cytopenia multilineage dysplasia with ringed sideroblasts (RCMD + RS)?
171
**_Myelodysplastic syndromes:_** What is are the blood features and bone marrow features of Refractory Anaemia with excess blasts 1 (RAEB I)?
172
**_Myelodysplastic syndromes:_** What is are the blood features and bone marrow features of Refractory Anaemia with excess blasts 2 (RAEB II)?
173
**_Myelodysplastic syndromes:_** What is are the blood features and bone marrow features of MDS with q5 deletion?
174
**_Myelodysplastic syndromes:_** What is are the blood features and bone marrow features of Myelodysplasia syndrome unclassified?
175
**_Myelodysplastic syndromes:_** What are the clinical features of Myelodysplastic Syndromes?
176
**_Myelodysplastic syndromes:_** What is a redudant term used for Myelodysplastic Syndromes?
177
**_Aplastic Anaemia:_** What is the definition of Aplastic Anaemia?
178
**_Aplastic Anaemia:_** What is the classification of Aplastic Anaemia?
179
**_Aplastic Anaemia:_** What is the management of Aplastic Anaemia?
180
**_Aplastic Anaemia:_** What is/are the genetics, epidemiology and symptoms of Fanconi Syndrome?
181
**_Aplastic Anaemia:_** What is/are the genetics and symptoms of Dyskeratosis Congenita?
182
**_Aplastic Anaemia:_** What is/are the genetics and symptoms of Schwamman-Diamond Syndrome?
183
**_Aplastic Anaemia:_** What are symptoms of Diamond-Blackfan Syndrome?
184
**_Aplastic Anaemia:_** What are the symptoms of Aplastic Anaemia?
185
**_Aplastic Anaemia:_** What is Aplastic Anaemia closely linked to?
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Year 5 Alex's Path total (5 decks)

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