HISTOPATH / MT LAWS Flashcards
Hypertension and aortic valve disease can lead to which type of cellular adaptation?
Pathologic Hypertrophy
Imperforate anus is an example of which of the following abnormalities in cell growth?
Atresia
Type of pathologic atrophy that may develop secondary to pressure atrophy?
Vascular Atrophy
Secondary change in somatic death important in establishing time of death?
Algor Mortis
Removing part of a liver can lead to _
Compensatory Hypertrophy
May also be referred to as “atypical metaplasia”
Dysplasia
In ____, affected cells microscopically appears ghostly.
Coagulative Necrosis
Brain infarct is an example of which of the following types of necrosis?
Liquefactive Necrosis
Autopsy technique that involves “en bloc” removal of organs.
Anton Ghon
Most common antibody label in immunohistochemistry.
Enzyme Label - Horseradish Peroxidase
Secondary change in somatic death that occurs 2-3 hours after death.
Rigor Mortis
Necrosis type in TB and lymphoid granuloma.
Caseous Necrosis
The cellular infiltrate in acute inflammation
Neutrophils
Microscopic changes in reversible injury:
1. karyorrhexis
2. fatty change
3. pyknosis
4. cellular swelling
2 and 4
True of necrosis except:
A. death of single cell in cluster of cells.
B. cell swelling
C. there is inflammation in neighboring tissues.
D. cellular contents leak out
Death of a sjngle cell in a cluster of cells
Cell adaptation mechanism characterized by adult-to-adult cell transformation
Metaplasia
Change in cell shape, size, and orientation characterize which cellular adaptation mechanisms?
Dysplasia
Type of necrosis seen in acute pancreatitis
Fatty Necrosis
In IHC, use of chromogen diaminobenzidine will result in which of the following end color?
Brown
Observation of 50-75% differentiated and 25% undifferentiated cells may be reported as __ in the Broder’s classification
Grade II
Decrease in thymus size during puberty may be classified as what type of cellular adaptation?
Physiologic Atrophy
Complete non-appearance of organ is termed ___
Agenesia
Autopsy technique that involves “in situ” dissection of organs.
Carl Rokintansky
Organs are removed en-masses is done in which of the following autopsy techniques?
Maurice Letulle
Developmental defect wherein the affected organs shows no resemblance to normal mature structure is
Aplasia
Apoptosis is characterized by all of the following except:
A. Intact cell outline
B. Inflammation
C. Cell Shrinkage
D None of these
Inflammation (Seen in necrosis only)
Purplish discoloration of skin in somatic death is termed __
Livor Mortis
Which may be considered to establish time of patient’s death?
A. Putrefaction
B. Algor Mortis
C. Rigor Mortis
D. Livor Mortis
Algor Mortis
Pain as one of the cardinal signs of inflammation is termed ___
Dolor
Solid organs like spleen and kidney may undergo which type of necrosis especially when the action of hydrolytic enzymes is blocked.
Coagulative Necrosis
Pre-neoplastic lesion is other term for which cellular adaptation mechanisms?
Dysplasia (Atypical Metaplasia)
Ciliated columnar cells lining the bronchi transforming into squamous epithelium due to excessive cigarette smoking is an example of ___
Metaplasia