Histopath Flashcards

1
Q

Signet ring cells + linitis plastica

A

Gastric Carcinoma

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2
Q

Perl’s Prussion Blue stain

A

Haemachromatosis

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3
Q

Solar elastosis

A

Actinic keratosis

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4
Q

Congo Red stain

A

Amyloidosis

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5
Q

Heliotrope rash

A

Dermatomyositis

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6
Q

Anti-mitochondrial antibodies

A

Primary biliary cirrhosis

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7
Q

Shepherd’s crook deformity

A

Varus angulation in fibrous dysplasia

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8
Q

‘Chinese letters’ bone formation

A

Fibrous dysplasia

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9
Q

Codman’s triangle

A

Osteosarcoma or Ewing’s sarcoma

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10
Q

‘Cotton wool’ calcification

A

Enchodroma

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11
Q

Anti-topoisomerase antibodies aka anti-Scl-70 antibodies

A

Systemic scleroderma (also CREST to a lesser degree)

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12
Q

Inter-cellular prickles within the lungs

A

Squamous cell carcinoma

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13
Q

Dermatitis herpetiformis

A

Coeliac disease

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14
Q

Needle-shaped crystals which are negatively birefringent under polarised red light

A

Gout (urate)

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15
Q

Red cell casts

A

Glomerulonephritis or vasculitis

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16
Q

White cell casts

A

Pyelonephritis

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17
Q

Kayser-Fleischer rings

A

Wilson’s

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18
Q

Anti Double-stranded DNA

A

SLE

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19
Q

Nutmeg liver

A

Congestive heart failure

20
Q

St Vitus Dance

A

Rheumatic heart disease

21
Q

F508 mutation

A

Cystic Fibrosis

22
Q

Biospy of the gastrointestinal wall reveals…

non-caseating granulomas

or transmural inflammation

or skip lesions and fistulae

A

Crohn’s

23
Q

Biopsy of the gastrointestinal tract reveals villous atrophy

with crypt hyperplasia.

A

Coeliac disease

24
Q

salmon-pink plaques with a

silver– white scale

A

Psoriasis

25
Q

‘Oat cell’ (lung cancer)

A

Small cell carcinoma

26
Q

Apple-green birefringence under polarized light and Congo red stain

A

Amyloidosis

27
Q

Gottron papules

A

Dermatomyositis

28
Q

Calcium pyrophosphate crystals, polygonal under polarised light

A

Pseudogout

29
Q

Extra-GI manifestations of arthritis, ankylosing spondylitis, stomatitis, uveitis, pyoderma gangenosum, erythema nodosum

A

Crohn’s disease

30
Q

Anti-tissue transglutaminase antibody, anti-gliadin antibodies, and anti-endomysial antibodies

A

Coeliac disease

31
Q

IgA deficiency may lead to false negative

A

Anti-TTG for Coeliac disease

32
Q

‘Leather bottle’ stomach

A

Gastric carcinoma

33
Q

Aflatoxin / Aspergillus

A

Hepatocellular carcinoma

34
Q

Solar elastosis with focal parakeratosis

A

Actinic (solar) keratosis

35
Q

Aschoff bodies and Anitschkow cells

A

Rheumatic heart disease

36
Q

Haemoptysis + haematuria

A

Anti-GBM disease aka Goodpasture’s syndrome

37
Q

‘Muddy casts’

A

Acute Tubular Necrosis

38
Q

Breast mouse

A

Fibroadenoma

39
Q

Which Dylan Thomas novel is set in the fictional town of ‘llareggub’?

A

Under Milk Wood

40
Q

Hodgkin’s lymphoma with best prognosis

A

Lymphocyte Predominant - best

Lymphocyte depleted - worst

41
Q

Copper carrying protein deficient in Wilson’s disease

A

Caeruloplasmin

42
Q

1st line investigation for Coeliac

A

Tissue transglutaminase IgA

43
Q

MIC2 (CD99) antibody

A

Ewing’s sarcoma

44
Q
A

Osteoid osteoma

45
Q

‘Sunburst’ appearance on X-ray

A

Osteosarcoma / Ewing’s sarcoma

46
Q

Most common form of thyroid cancer

A

Papillary (75-85%), followed by Follicular, then Medullary, then Anaplastic