Histopath Flashcards
Signet ring cells + linitis plastica
Gastric Carcinoma
Perl’s Prussion Blue stain
Haemachromatosis
Solar elastosis
Actinic keratosis
Congo Red stain
Amyloidosis
Heliotrope rash
Dermatomyositis
Anti-mitochondrial antibodies
Primary biliary cirrhosis
Shepherd’s crook deformity
Varus angulation in fibrous dysplasia
‘Chinese letters’ bone formation
Fibrous dysplasia
Codman’s triangle
Osteosarcoma or Ewing’s sarcoma
‘Cotton wool’ calcification
Enchodroma
Anti-topoisomerase antibodies aka anti-Scl-70 antibodies
Systemic scleroderma (also CREST to a lesser degree)
Inter-cellular prickles within the lungs
Squamous cell carcinoma
Dermatitis herpetiformis
Coeliac disease
Needle-shaped crystals which are negatively birefringent under polarised red light
Gout (urate)
Red cell casts
Glomerulonephritis or vasculitis
White cell casts
Pyelonephritis
Kayser-Fleischer rings
Wilson’s
Anti Double-stranded DNA
SLE
Nutmeg liver
Congestive heart failure
St Vitus Dance
Rheumatic heart disease
F508 mutation
Cystic Fibrosis
Biospy of the gastrointestinal wall reveals…
non-caseating granulomas
or transmural inflammation
or skip lesions and fistulae
Crohn’s
Biopsy of the gastrointestinal tract reveals villous atrophy
with crypt hyperplasia.
Coeliac disease
salmon-pink plaques with a
silver– white scale
Psoriasis
‘Oat cell’ (lung cancer)
Small cell carcinoma
Apple-green birefringence under polarized light and Congo red stain
Amyloidosis
Gottron papules
Dermatomyositis
Calcium pyrophosphate crystals, polygonal under polarised light
Pseudogout
Extra-GI manifestations of arthritis, ankylosing spondylitis, stomatitis, uveitis, pyoderma gangenosum, erythema nodosum
Crohn’s disease
Anti-tissue transglutaminase antibody, anti-gliadin antibodies, and anti-endomysial antibodies
Coeliac disease
IgA deficiency may lead to false negative
Anti-TTG for Coeliac disease
‘Leather bottle’ stomach
Gastric carcinoma
Aflatoxin / Aspergillus
Hepatocellular carcinoma
Solar elastosis with focal parakeratosis
Actinic (solar) keratosis
Aschoff bodies and Anitschkow cells
Rheumatic heart disease
Haemoptysis + haematuria
Anti-GBM disease aka Goodpasture’s syndrome
‘Muddy casts’
Acute Tubular Necrosis
Breast mouse
Fibroadenoma
Which Dylan Thomas novel is set in the fictional town of ‘llareggub’?
Under Milk Wood
Hodgkin’s lymphoma with best prognosis
Lymphocyte Predominant - best
Lymphocyte depleted - worst
Copper carrying protein deficient in Wilson’s disease
Caeruloplasmin
1st line investigation for Coeliac
Tissue transglutaminase IgA
MIC2 (CD99) antibody
Ewing’s sarcoma
Osteoid osteoma
‘Sunburst’ appearance on X-ray
Osteosarcoma / Ewing’s sarcoma
Most common form of thyroid cancer
Papillary (75-85%), followed by Follicular, then Medullary, then Anaplastic