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GU Week 3 > Histology of Male Repro - Checked and Complete > Flashcards

Histology of Male Repro - Checked and Complete Flashcards

1
Q

Define Kartagener’s Syndrome

A

Immobitile Cilia of Sperm (also cilia in larynx, other places)

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2
Q

What is the relative pH of semen?

A

Alkaline

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3
Q

Define path of sperm from production to ejaculation.

A

Seminiferous Tubules

Tubuli Recti

(Rete testis)

Efferent ducts

Epididymis

Vas Deferens

Ejaculatory Duct

Prostatic Urethra

Membranous Urethra

Penile Urethra

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4
Q

Name the layers of the testis

A

Skin

Dartos Tunic

Cremaster

Tunica vaginalis (Parietal and Visceral)

Tunica albuginea

Tunica vasculosa

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5
Q

Name 3 parts of urethra in male

A

Prostatic

Membranous

Penile

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6
Q

Where are the Leydig cells found?

A

In between seminiferous tubules

(called interstitial cells of Leydig)

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7
Q

What is the main function of Leydig cells?

A

Testosterone production

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8
Q

How might you recognize Leydig cells histologically?

A

Polygonal

In between round tubules

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9
Q

What 2 cell types are found in seminiferous tubules?

A

Sertoli cells

**Spermatogenic cells **

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10
Q

What are the functions and secretions of the Sertoli cells?

A

Protect sprem from immune system

Nurture sprematogenic cells

Inhibin secretion (inhibits FSH)

synthesize androgen-binding protein (ABP) (under control of FSH)

Secrete Anti-mullerian hormone

Phagocytose excess cytoplasm

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11
Q

Describe the function of ABP

A

Bind and allow accumulation/concentration of testosterone (normally lipophilic and moves freely) in seminiferous tubules

This encourages spermatogenesis

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12
Q

Which hormone regulates FSH (not GnRH)? Which hormone does FSH regulate?

A

Inhibin regulates FSH

FSH regulates ABP

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13
Q

Where do you find immature spermatogonia vs mature spermatids in the seminiferous tubules?

A

Immature Sprematogonia on bottom

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14
Q

What are the 5 categories of intermediates in spermatogenesis?

A

Spermatogonia

1ry spermatocyte

**2ndry spermatocyte **

** Spermatids**

** Spermatocyte **

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15
Q

What are the3 phases in spermatogenesis?

A

Spermatogonial phase

spermatogonia form primary spermatocytes

**Spermatocyte phase **

primary spermatocytes undergo two meiotic divisions to produce spermatids

Spermatid phase

spermatids differentiate into mature sperm cells

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16
Q

How can you identify rete testis histologically?

A

Apical cilium with big gaps near seminiferous tubules

17
Q

Define efferent tubules

A

A collection of 10-20 tubules leading from the rete testis to the epididymis

18
Q

What are secretions of the prostate?

A

Prostatic acid phosphatase (PAP)

fibrinolysin

** citric acid**

Prostate-specific antigen (PSA) (serine protease)

19
Q

What is the easiest way to recognize the prostate histologically?

A

Presence of calcifications

GU Week 3 (5 decks)

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