Histology of LNs, Thymus, MALT, Spleen

Question 1

What differentiates active from inactive lymph nodes?

Answer 1

Active lymph nodes have lighter germinal center in follicles full of replicating B cells

Question 2

Function of Spleen

Answer 2

Contains IgG sensing macrophages that remove old RBCs and lymphocytes that detect infections

Question 3

Function of Thymus

Answer 3

Site of T-cell maturation, thymocytes checked for self-reactivity

Question 4

Lymph Node Function

Answer 4

concentrated areas of lymphocytes where APCs can stimulate large adaptive response

Question 5

Function of MALT

Answer 5

areas of lymphocyte congregation at body’s borders to protect from invading pathogens