histology of epithelial cells Flashcards

1
Q

what do all epithelial cells do

A

act as lining cells

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2
Q

what are endothelial cells in regards to epithelial cells

A

endothelial cells are a specialised version of epithelial cells, as they are the cells that line the blood vessels making up the circulatory system

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3
Q

what keeps all epithelial cells in place

A

an adhesion to its underlay called the basement membrane

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4
Q

name the 4 major functions of epithelial cells

A

barrier/protection, absorption, lubrications, and movement

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5
Q

what are the two types of passage through epithelial cell junctions (from the outside to inside environment) called

A

paracellular and transcellular

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6
Q

what are tight junctions in epithelial cells and what do they do

A

the proteins that stick epithelial cells together in their lateral membranes - they control the passage of substances between cells

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7
Q

in epithelial cell nomenclature what does the word simple mean

A

one cell thick

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8
Q

in epithelial cell nomenclature what does the word stratified mean

A

layered

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9
Q

in epithelial cell nomenclature what does the word pseudostratified mean

A

false layered - they appear layered but are actually one cell thick

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10
Q

in epithelial cell nomenclature what does the word cuboidal mean

A

square cell

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11
Q

in epithelial cell nomenclature what does the word columnar mean

A

tall cell

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12
Q

in epithelial cell nomenclature what does the word squamous mean

A

flattened cell

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13
Q

in epithelial cell nomenclature what does the word transitional mean

A

changeable/ dynamic

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14
Q

where is the only place transitional cells are found

A

the bladder

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15
Q

describe simple squamous epithelial cells

A

cells are flat and spread out, meaning they have a large surface area in contact with the exterior environment and the basement membrane - anchoring is strong

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16
Q

give an example of where simple squamous epithelial cells would be found

A

anywhere where easy transmembrane movement is advantageous e.g. in the alveoli

17
Q

describe simple cuboidal epithelial cells

A

they have an increased cytoplasmic volume when compare to squamous cells, meaning they are capable of fulfilling some more complex roles such as secretion

18
Q

where are simple cuboidal epithelial cells found

A

in glands which specialise in secretion e.g. salivary glands

19
Q

describe simple columnar epithelial cells

A

cells that are taller than they are wide, with a nucleus that is polarised towards the basement membrane

20
Q

what is the function of simple columnar epithelial cells

A

they are very capable of dealing with wear and tear, and secreting large amounts of substances

21
Q

give an example of where simple columnar epithelial cells may be found

A

in the lining of the stomach - protects from the acid
in the lining of the intestines - secretions for lubrication

22
Q

describe stratified squamous epithelial cells

A

multi-layered epithelium in which the outermost layer are flat and scale-like - the lower layers may be different shaped but we name off of the most apical layer

23
Q

give an example of where stratified squamous epithelial cells can be found

A

surfaces that are subject to high levels of mechanical abrasion e.g. the skin

24
Q

name the two varieties of stratified squamous epithelial cells and how they differ

A

dry (keratinising stratified squamous epithelium) - called keratinocytes as they produce a tough protein called keratin that causes the top layer of cells to die, making the dry
wet (non-keratinising stratified squamous epithelium) - called non-keratinising epithelial cells as they produce a moist surface with the absence of keratin, keeping the cells alive

25
what is another difference regarding wet and dry stratified squamous epithelial cells regarding nuclei
dry = no nuclei wet = nuclei
26
describe pseudostratified columnar epithelial cells
all of the cells in the layer are in contact with the basement membrane but due to the misaligned nuclei the cells appear stratified
27
where are pseudostratified columnar cells common and why
in the upper respiratory system as the flexibility of columnar cells allows the cells to move during the ins and outs of breathing
28
describe transitional epithelial cells
a stratified epithelium in which the shape of the cells at the luminal layer may be difficult to discern due to the change in shape of cells
29
what is the difference in appearance of transitional epithelial cells during relaxation and stretching
apical cells may appear rounded/cuboidal when the organ is relaxed, and flattened/squamous when it is stretched
30
what do ciliated epithelial cells contain
hair like projections on their surface called cilia
31
where are ciliated epithelial cells most common and what do they do
in the respiratory tract where they move mucus laden with dust or microbes away from the lungs to the upper regions so they can be coughed or sneezed out
32
what do epithelial cells with microvilli contain
finger like protrusions on their surface called microvilli
33
what is the major difference between cilia and microvilli
cilia move, whereas microvilli do not as their main role is absorption rather than locomotion
34
what is a brush boarder referring to
where microvilli are extremely tightly packed so that they give the appearance of a fuzzy band
35
where is the most common place to find epithelial cells with microvilli and why
in the intestine as the surface area increase allows for maximum absorption of nutrients from the gut
36
what are goblet cells
modified columnar epithelial cells that synthesise and secrete mucous
37
why do goblet cells receive their name
their shape resembles a drinking goblet
38
where can goblet cells be found and why
in the respiratory and gastrointestinal tracts as they help with lubrication