Histology of Cv System Flashcards
describe the structure of capillaries
it is lined by endothelial cells
has a thin basal lamina
pericytes (help maintain viability of endothelial cells)
-7-9 in diameter
what are the three different types of capillaries
continous
fenestrated
sinusoidial
capillaries that have tiny
openings, or pores.
* Allow larger molecules and
proteins to move from your blood
into organs and glands. (eg.
Intestine)
fenestrated
capillaries are tiny
blood vessels that deliver blood,
nutrients and oxygen to our cells.
* Contains pinocytic vesicles
* Present in the skin, lungs, and
blood-brain barrier
continuous
larger
than other capillaries and have a
discontinuous endothelium. (eg.
Liver, spleen, bone marrow)
* Kupffer cells are present in the
lumen
sinusoidal
what are some capillary exchange mechanisms
open pores/ gaps
diffusion,filtration, vesicular transport “transcytosis”
transendothelial channels
what are some secretory and metabolic functions of endothelial cells
Adhesion molecules
(diapedesis)
▪Produce vasoactive
compounds
▪ NO for vasodilation,
▪endothelin for
vasoconstriction
▪ Anti-thrombogenic
factors
▪Metabolic conversions
(angiotensin I to II)
i.e. vasoconstriction
structure includes endothelium subendothelial layer and internal elastic lamina
tunica intima
structure includes smooth muscle and elastic fibers
external elastic lamina
tunica media
structure includes collagen fibers
tunica externa
this structure is thicker in arteries and thinner in veins
tunica media
this structure is thinner in arteries and thicker in veins
tunica adventitia
phentotype is Branched networks Tapered in each end Long & cylindrical,
between cells
Single nucleus Single nucleus Multi-nucleated
Straited with Non-straited Straited
intercalated discs
cardiac muscle
tapered in each end
single nucleus
non straited
smooth muscle
long and cylindrical
multi nucleated
straited
skeletal muscle