Histology: Connective tissues Classification (subtype: connective tissue proper) Flashcards
Describe the common Connective Tissue structural characteristics
Mainly supports and connects tissue
cells are far a part, separated by an extarcellular matrix (ex. outside a bone)
- extraceullular material, gives CT subtypes their identifying characteristics
variable vascularity (some has blood vessels and some dont)
Describe how the cells of connective tissues are named, giving examples
blast, cyte and clast
blast: creates a matrix e.g osteoblast, chondroblast, fibroblast
Cyte: maintains matrix e.g osteocyte, chondrocyte, fibrocyte
Clast: breakdown matrix e.g osteoclast (no cartiladge, or CT proper)
- only found in bone (very hard matrix)
List the components of connective tissue matrix
Fibres (proteins) and Ground substance
Fibres (proteins)
matrix composition of the connective tissue
- collagen fibres (for strength)
- elastic fibres (containing elastin - allow stretch and recoil) Analogy: like a rubber band if let go = back to original shape
- reticular fibres (forming network - e.g CT part of basement membrane)
Collagen fibres
Fibres (a part of the matrix composition for CT)
used for strength
Fibres found in areolar, dense regular, dense irregular, bones and cartilage matrix’s
Elastic Fibres
Fibres (a part of the matrix composition for CT)
containing Elastin - allow stretch and recoil
Found in Areolar, Cartilage tissue matrix
Reticular fibres
Fibres (a part of the matrix composition for CT)
forming networks ex) CT a part of basement membrane
Ground substance
Where is it found? What is the purpose of a ground substance? What is it composed of and give examples
A part of matrix composition of connective tissue
unstructure material surrounding extracellular fibres and cells
Composed of: water and large organic molecules = large proteoglycans (contain proteins and polysaccarides
e.g hyaluronic acid, chondroitin sulphate
Proteoglycan
In the Ground subtance (a part of the matrix composition)
Proteodoglycan are large organic molecules, which contain proteins and polysaccarides
How is connective tissue classified? List the subtypes of connective tissue
Classification mainly by matrix composition (recall: fibres(proteins) and ground substance)
Subtypes of Connective tissue:
1. connective tissue proper - actually connects! (loose CT (subtypes: areolar CT and adipose) and dense CT ( subtypes: dense regular and dense irregular))
2. cartilage
3. Bone
4. blood
osteoblast,chondroblast and fibroblast
Cells that are a part of connective tissues that create matrix
osteocytes, chondrocytes and fibrocytes
Cells that are apart of connective tissue that maintain matrix
osteoclast
breaks down matrix (only found in bones;very hard matrix)
Characteristics of Connective Tissue Proper
Name each subtype and explain their characteristics
Cells = fibroblast (creates matrix)/fibrocytes(maintains matrix) except adipose tissue (adiposecytes)
Types of connective tissue proper
1.Loose CT (areolar and adipose)
* Areolar CT (highly vascular = provide nutrients)
* Matrix: loosely arranged collagen and elastic fibres,surrounded by ground substance, hyaluronic acid
* e.g lamina propria= special name to a CT part of mucous membrane
* Adipose (highly vascular)
* very little matrix
* cells large (adipocytes) - store triglygercides (tissue looks like chickenwire)
2.Dense CT (dense regular and dense irregular)
Many fibres (also known as fibrous CT)
little ground substance
poorly vascular
* Dense regular (fibrous CT = many fibres)
* collagen fibres running in same direction
* e.g tendons (muscle->bone join), ligaments (bone->bone)
* Dense irregular
* collagen fibres arranged irregularly ability to move around, provide flexibility
* e.g dermis of skin
Loose Connective Tissue
Loose CT is a subtype of connective tissue proper
Two types of Loose CT: Areolar connective tissue and Adipose Tissue
Areolar CT (highly vascular = provide nutrients)
* loosely arranged collagen and elastic fibres surrounded by ground substance (hyraulonic acid)
* e.g lamina propria = special name to a CT part of mucous membrane
Adipose (highly vascular)
* very little matrix
* cells large (adipocytes) - store triglygercides (tissue looks like chickenwire)