Histology Flashcards
Layers of the heart
- Epicardium
- Myocardium
- Endocardium
Epicardium
Simple squamous epithelium (mesothelium)
Thin layer of (fibroelastic) CT and fat
Myocardium
Cardiac muscle fibres (striated) in different planes to close down lumen chamber
- Central rounded nuclei
- Intercalated discs
- Rich capillary bed
Endocardium
Simple squamous epithelium that lines the atria, ventricles and valves
- Underlying basement membrane
- Small layer of loose CT and adipose tissue
Elastic aorta examples
Aorta
Pulmonary trunk
Elastic artery function
Large conducting vessels that act as pressure reservoirs by stretching during systole
- Pressure falls during diastole and the artery recoils maintaining pressure on the blood
Elastic artery histology
Vasa vasorum in T. adventitia
Elastic fibre laminae (elastin secreted by smooth muscle cells) in T. media
Single layer of endothelial cells with elastin rich collagen supporting layer in T. intima
- Fibroblasts and myointimal cells
- Accumulate lipid with ageing
Muscular artery function
Distributing vessels
Muscular artery histology
T. adventitia contains collagen and elastin.
- External elastic layer
Thick T. media primarily smooth muscle (no elastic laminae), elastin and collagen
- Internal elastic layer
T. intima is flattened endothelial cells
Arteriole function
Terminal branches which supply blood to capillary bed (local) and control blood pressure (systemic)
Arteriole histology
T. adventitia merges with surrounding tissue
- No EEL
Only 1-2 layers of smooth muscle for T. media
- No IEL
T. intima is simple squamous epithelium
Rich sympathetic innervation
Diameter: 100-300 um
Capillary function
Main site of exchange for nutrients and gases
- Low blood pressure
- Very thin-walled
Capillary histology
T. Intima only
Diameter 3-4 um
- Endothelium on BM
Pericytes
Incomplete layer of cells surrounding BM have contractile properties to control blood flow
Continuous capillaries
Materials must pass through cell or between cell
Selective transport mechanisms
- E.g. muscle