histo+physio Flashcards

1
Q

epineurium

A

surrounds each nerve bundle (of entire nerve)

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2
Q

perineurium

A

surrounds each fascicle of nerve groups

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3
Q

endoneurium

A

surrounds each axon (fiber) > goruped to form fascicle

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4
Q

schwann cells

A

very visible on l/s and prod the myelin for nerve fibers IN PNS

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5
Q

nodes of ranvier

A

facilitate nerve impusle transmission

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6
Q

cortex of brain made up of

A

diffuse arrangement of neurons

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7
Q

neuclus is

A

discrete arrangement of neuronal cells

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8
Q

coloumn is

A

arrangement of cells in spinal cord

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9
Q

tract or fascicle is

A

defined bundle of axons

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10
Q

neuroglia

A

astrocytes
oligodend
microglia
ependymal

supporting cells to the neurons

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11
Q

astrocytes char

A

most common glial cells in grey matter
long branched processes - star shape

processes end on non synaptic areas of neurons OR blood vessels

this termination on blood vessels create BB Barrier

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12
Q

astrocytes func

A

metab exchange bet neuron and blood
regulate int environ of cns

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13
Q

types of astrocytes

A

fibrous- white matter, few STRAIGHT cytoplasmic processes

protoplasmic- grey matter, many BRANCHED processes

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14
Q

oligodendrocytes char + func

A

resp for myelination in CNS
large cells > invest up to 50 axons

smol rond nucl
cyto doesnt stain

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15
Q

microglia func + char

A

smol cells
elong nucl with little cyto
migratory

transform into LARGE MACROPH for protective role

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16
Q

ependymal cells char + func

A

epith like cells that line ventricles
cuboidal or low columnar

tightly bound
NO BM
presence of cilia and microvilli

17
Q

3 layers of grey matter in cblm

A

PPG
outer- plexiform/molecular layer
middle-purkinjee layer
inner- granular layer

18
Q

plexiform layer of cblm

A

outer
very few cells, many synapses
contains stellate and basket cells

19
Q

purkinjee layer of cblm

A

middle
contains hugr purkinjee cells

dendrites transverse molecular layer and reach surface
axons of purkinjee cells are only EFFERENT

20
Q

granular layer of cblm

A

innner
small dense cells
dark stained nucl

21
Q

purkinjee cell

A

literally looks like an onion between the granular layer (darker) with dendrites that reach upwards to surface through the molecular layer

22
Q

pyramidal cells

A

found in cerebral cortex
trianglular
thick branching dendrite that extends to surface

23
Q

appearance of non pyramidal cerebral cortex cells

A

stellate - star shaped
horizontal - outer layer orientate parr to surface
fusiform - spindle shaped orientated perp to surface
cells of martinotti - small polygonal with few short dendrites

24
Q

excitatory ntrans moa

A

slight depol by opening na+ channel
leads to na influx
causes excitatory postsynaptic potential to develop ap in axon

25
Q

inhibtory ntrans moa

A

opening k+ channels in postsynaptic memb
leads to k+ efflux
hyperpol
causing ihibitory postsynaptic potential
ap is not generated

26
Q

inactivation of ntrans mechanisms

A

diffuses out of synaptic cleft where it has no action
destroyed by specific enzymes
engulfed by astrocytes
reuptake into axon terminal (carrier prot)