Histo - Ear Flashcards

1
Q

What are the 3 components to the Ear?

A
  1. External ear
    • takes in sound
  2. Middle ear
    • ossicles (bones)
      • transmit sound from air –> fluid
  3. Internal ear
    • fluid moving causes nerves to fire
      • hearing
    • equilibrium
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2
Q

Name the parts of the ear

A
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3
Q

What are the components of the External Acoustic Meatus?

A
  • Tympanic membrane (eardrum)
  • Hair follicles
  • 2 Types of Glands (in submucosa)
    1. Sebacous glands (SG)
    2. Ceruminous glands (CB)
      • modified apocrine sweat glands
        • both secrete ear wax
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4
Q

What are the components of the Internal Ear?

A
  • Bony Labrynth
  • Membrenous Labyrnth
  • Ampullae
  • Round Window
  • Oval Window
  • Apex of Cochlea
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5
Q

Tympanic Membrane

A
  • Fibroelastic CT
  • Outer part = SSK
  • Inner part = Simple cuboidal
    • sound in air –> vibrations of tympanic membrane to transmit to middle ear
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6
Q

Middle Ear

A

Tympanic Cavity

  • Air filled space
    • btw eardrum & bone of internal ear
  • Auditory tube (Eustachian tube)
    • communicates w/ pharynx anteriorly
    • balances air pressure in middle ear
  • Interacts w. mastoid cavities (air spaces in temporal bone) posteriorly
  • In medial part = 2 regions w/ no bones
    1. oval window
    2. round window

Bones (Ossicles)

  • 3 bones
    • Malleus
    • Incus
    • Stapes

Muscles - protect oval window/inner ear from loud sounds

  • Tensor tympani
  • Stapedius
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7
Q

What is a middle ear infection?

A

Otitis Media (ear infection)

  • Caused by infection that come through the Auditory Tubes from respiratory tract
    • more common in children
      • small & short tubes
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8
Q

Inner Ear

A

Bony Labyrinth

  • contains perilymph

Vestibule

  • saccule & utricle within

Semicircular canals

  • has semicircular ducts within

Cochlea

  • has cochlear duct within
  • spiral/cochlear ganglion & process of CN VIII w/in modiolus

Membranous Labyrinth (sensory region w/ hair cells)

  • contains endolymph
  • surrounded by bony labyrinth

2 connected sacs

  • Utricle
  • Saccule

3 semicircular ducts

  • continuous w/ utricle
  • cristae ampullares in each duct

Cochlear duct (organ of hearing)

  • continuous w/ saccule
  • contains SPIRAL ORGAN of CORTI
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9
Q

Inner Ear Fluids

A

Perilymph (Bony Labyrinth)

  • similar to CSF & ECF
    • little protein
  • protects membranous labyrinth

Endolymph (Membranous Labyrinth)

  • high in K+
  • low in Na+
  • similar to ICF
  • produced by STRIA VASCULARIS
    • vascular epithelium
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10
Q

How does the Vestibular Organ sense equilibrium?

A

3 semicircular canals

  • superior
  • horizontal
  • posterior

2 sacs (otolith organs)

  • saccule
  • utricle
    • both are CT lined by simple squamous epithelium
    • bound to periosteum of bony labryinth

Ampullae are present at the connection of the canals w/ utricle.

  • Maculae = present w/in walls of sacs
    • thickeningns w/ many hair cells
    • columnar neuroepithelial cells
      • supporting cells & synaptic connections
      • innv. by vestibular n. (VIII)

Function:

  • Detect gravity & moving endolymph
    • perpendicular to each other
  • Hair cells have a layer over them = otolithic layer
    • gelatinous
    • proteoglycans
    • otoliths embedded
      • CaCO3 & protein
      • mending of kinocilia
  • Hair cells have stereocilia & single kinocilum
  • Basal part of hair cells have synaptic connections w/ nerve fibers
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11
Q

Hair Cells in Vestibular Maculae

A
  • Mechanoelectrical transducers
    • monitor static position
    • monitor linear acceleration
    • helps maintain equilibrium
  • Single Kinocilium
    • rigid
  • Multiple stereocilia
    • rigid
    • rows that DECREASE in length
  • 2 Types of hair cells
    • Type I:
      • rounded clels
      • nerve calyx around them
    • Type II
      • columnar cells
      • typicall synapses
    • **BOTH have efferent fibers that connect w/ them on their afferents
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12
Q

Mechanotransduction in Hair Cells in Maculae

A
  • Bending of stereocilia of macular hair cells causes:
    • changes to ion channels in the TIPS of stereocilia
    • TOWARD kinocilium = DEPOLARIZATION
      • open channels
    • AWAY kinocilium = HYPERPOLARIZATION
      • channels close
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13
Q

What is this?

A

Maculae

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14
Q

Semicircular Ducts

A
  • 3 semicircular ducts
    • come from & return to the utricle
  • different orientations to each other
  • each has an AMPULLA (enlarged space)
    • crista ampullaris = structures within the ampulla wall
      • has hair cells & support cells
        • similar to those in maculae
      • perpendicular to long axis of duct
      • protrudes –> duct
      • has cupola (NOT OTOLITHIC LAYER)
        • proteoglycan layer
        • NO otoliths
        • thicker than otolithic layer
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15
Q

Hair Cells in Cristae Ampullares

A
  • Mechanoelectrical transducters
    • signal by depolarization & hyperpolarization
  • Detect rotation of head
    • endolymph moves w/in duct & deflects hair cells
  • CNS detects input from all 3 sets of cristae hair cells
    • interprets the input as head rotation
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16
Q

What is this?

A

Cristae Ampullaris

17
Q

What is this?

A

Vestibular System

18
Q

What are the 3 main Issues of the Vestibular System?

A
  1. Motion sickness
    • overstimulation of maculae of utricle
    • due to repetitive changes in linear acceleration & changes in direction
  2. Vertigo
    • overstimulation of cristae ampullares of semicircular ducts
  3. Meniere disease
    • vestibular neuritis (inflammation)
    • inreased pressure in membranous labyrinth
      • endolymphatic hydrops
      • causes rupture, so endolypmh leask into perilymph!
19
Q

Cochlea

A

Contains 3 parallel regions (scalae)

  • 2 3/4 turns w/in cochlea

Scala media/cochlear duct - middle of scalae

  • contains ENDOLYMPH
  • contains organ of Corti
    • organ of hearing
    • hair cells –> transduce sound waves into hearing
  • contain stria vascularis
    • secrete ENDOLYMPH
    • vascularized epithelium
  • bound by basilar & vestibular membrane

scala vesibule & tympani

  • contain PERILYMPH
  • one tube –> coiled
    • continuous at the apex = helicotreme
20
Q

What is this?

A
21
Q

What is this?

A

Organ of Corti

  • Sits on BASILAR MEMBRANE
    • 2 sets of hair cells
      • support cells = PHALANGEAL CELLS
      • pillar cells = INNER TUNNEL
  • Phalangeal cells
    • both inner & outer
      • support both types of hair cells & nerve endings
  • Pillar cells
    • keratin bundles
    • defines inner tunnel
22
Q

What is this?

A

Hair Cells in the Organ of Corti

Outer Hair Cells

  • 3-5 row
  • V-shaped set of steriocilia

Inner Hair Cells

  • single row
  • linear/shorter/stereocilia
  • MAIN HEARING RECEPTORS
  • MORE nerve endings!!

Apical part of cells = embedded in tectorial membrane

  • tectorial membrane = acellular
    • made of collagen & proteoglycans

BOTH:

  • innv by AFF bipolar neurons in SPIRAL GANGLION
  • have EFF nerve endings
  • hair cells = mechanoelectrical transducers
23
Q

What is this?

A

Tectorial Membrane

  • apical part of Organ of Corti
    • acellular membrane
    • made of collagen & proteoglycans
24
Q

Process of Hearing

A
  1. Sound waves vibrate the tympanic membrane
    • moves ossicles & oval window
  2. Energy transfers to PERILYMPH
    • pressure waves move along SCALA VESTIBULE
    • causes displacement of vestibular or basilar membranes –> thus ENDOLYMPH
  3. Activates nerve endings on the hair cells
  4. Communicates along CN VIII —> CNS
    • perceived sound it can interpret
25
Q

What is this?

A

Hair Cells in the Organ of Corti ‐ SEM

26
Q

What is this?

A

Spiral Ganglion

  • AKA: Cochlear ganglion
    • forms part of CN VIII
  • Within bony modiolus (center of cochlea)
  • BIPOLAR neurons
    • peripheral part = innv receptor cells (hair cells)
    • central part = enters modiolus