Histamine Related Disorders Flashcards

1
Q

Histamine Related disorders are which type of hyper sensitivity reaction

A

Type one

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2
Q

Urticaria involves EDEMA of

A

Dermis

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3
Q

Characteristic lesion of Urticaria

A

Wheal

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4
Q

Angioedema is also called as

A

Quincke’s disease

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5
Q

Type of edema in angioedema

A

Non pitting type

Seen in s/c tissue & submucosa

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6
Q

Time duration of acute and chronic urticaria

A

Acute <6 wks

Chronic > 6 wks

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7
Q

Dermographism is

A

Stroking of NORMAL SKIN with BLUNT OBJECT

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8
Q

Dermagraphism is a feature of

A

Chronic urticaria

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9
Q

White dermographism is seen in

A

Atopic dermatitis

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10
Q

Cholinergic urticaria occurs due to

A

Increase in core body temperature due to exercise or physical exertion

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11
Q

Hereditary Angioedema inheritance

A

Autosomal dominant

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12
Q

Defect in hereditary angioedema

A

C1 esterase inhibitor defect

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13
Q

C1 esterase inhibitor recombinant

A

ECALLANTIDE

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14
Q

Bradykinin B2 receptor antagonist

A

ICATIBANT

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15
Q

Cutaneous mastocytosis is aka

A

Urticaria pigmentosa

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16
Q

Darier sign is seen in

A

Cutaneous mastocytosis
Juvenile xanthogranuloma
All neonates

17
Q

Pseudodarier sign is seen in

A

Smooth muscle hamartoma

18
Q

Stain for mast cells

A

Toluidine blue

19
Q

CD marker of cutaneous mastocytosis

A

CD 117