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Derma > Basics > Flashcards

Basics Flashcards

1
Q

Total body weight of skin

A

16 kg

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2
Q

Layers of skin

A 
Stratum corneum 
Stratum lucidum
Stratum granulosum
Stratum spinosum 
Stratum basale
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3
Q

Histology of epidermis

A

Stratified squamous epithelium

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4
Q

Desmosomes are present in

A

Stratum SPINOSUN

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5
Q

LANGERHANS cells are present in

A

Stratum spinosum

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6
Q

Content of Langerhans cells

A

Birbeck granules

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7
Q

Markers of LAngerhans cells

A

S-100
CD 1a
CD 207

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8
Q

Melanocyte is present in

A

Stratum basale

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9
Q

Markers of melanocyte

A

S-100
Melan- A
HMB-45

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10
Q

Merkel cells are present in

A

St. Basale

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11
Q

Marker of merkel cell

A

Cytokeratin-20

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12
Q

Neutrophilic micro abscess is seen in

A

Psoriasis- Monroe microabscess ( st. Corneum)
-spongiform pustule of kogoj (st. Spinosum)
Dermatitis herpetiformis - papillary tip microabscess

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13
Q

Eosinophilic microabscess is seen in

A

Pemphigus vegetans

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14
Q

Atypical T cell abscess is seen in

A

Pautrier microabscess- ctcl

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15
Q

Petechiae size is

A

1-2mm

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16
Q

Purpura size Is

A

> 3mm

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17
Q

Ecchymoses size is

A

1-2cm

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18
Q

Erosion is

A

Loss of epidermis

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19
Q

Ulcer is

A

Loss of epidermis plus partial dermis

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20
Q

LANGERS line corresponds to

A

Orientation of collagen fibres in the skin

21
Q

BLASCHKOS lines correspond to

A

Represent lines of embryological development

22
Q

True NIKOLSKY sign is seen in

A

Pemphigus foliaceus
Pemphigus vulgaris
SSSS

23
Q

DIASCOPY in Lupus vulgaris

A

Apple jelly nodules

24
Q

Desmosomes are targeted in which diseases

A 
Pemphigus
Bullous impetigo
Hsv 
Ssss
Hailey hailey disease
Darier disease
25
Q

Lichenification is characterised by

A

Hyper pigmentation
Thickening of Skin
Exaggerated skin markings

26
Q

Layers of hair

A 
Hair shaft
Inner root sheath 
Outer root sheath
Glassy membrane
Connective tissue sheath
27
Q

Epidermis is derived from

A

Ectoderm

28
Q

Dermis is derived from

A

Mesoderm

29
Q

Lamellar granules are present in

A

St granulosum

30
Q

Desmosomes aka

A

Macula adherens

31
Q

Protein present in desmosomes

A

Desmoglein
Desmocollin
Desmoplakin

32
Q

Meissner corpuscle is present in

A

Papillary dermis

33
Q

Superficial vascular plexus of skin is present

A

Below papillary dermis

I.e btw papillary and reticular dermis

34
Q

Deep vascular plexus is present

A

Below reticular dermis

35
Q

Connective tissue of reticular dermis

A

Dense irregular

36
Q

Ratio of type 1 : type 3 collagen

A

8:1

37
Q

The colour of skin does not depend on

A

No. Of melanocyte

38
Q

2 types of melanin

A

Eumelanin

Pheomelanin

39
Q

Eumelanin is

A

Brown black pigment

Present in dark skin people

40
Q

Pheomelanin is

A

False melanin
Yellow-red pigment
Present in fair people

41
Q

Merkel cells aka

A

Haascheiban cells

42
Q

hemidesmosomal protein

A

BPag 1,2
K5/K14
Plectin

43
Q

Anchoring filaments proteins

A

Laminitis 5/332
Type 4 collagen
Nidogen

44
Q

Anchoring fibrils protein

A

Collagen 7

45
Q

Tzanck smear is fixed using

A

Formal-zenker solution

46
Q

Tzanck smear stain used

A

Giemsa

47
Q

Cutaneous pigmentation with telengiectasis is known as

A

Poikiloderma

48
Q

Indications for PUVA therapy

A 
Psoriasis 
Atopic dermatitis 
Vitiligo
Polymorphic light eruption 
CTCL

Derma (8 decks)

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