Basics

Question 1

Total body weight of skin

Answer 1

16 kg

Question 2

Layers of skin

Answer 2

Stratum corneum 
Stratum lucidum
Stratum granulosum
Stratum spinosum 
Stratum basale

Question 3

Histology of epidermis

Answer 3

Stratified squamous epithelium

Question 4

Desmosomes are present in

Answer 4

Stratum SPINOSUN

Question 5

LANGERHANS cells are present in

Answer 5

Stratum spinosum

Question 6

Content of Langerhans cells

Answer 6

Birbeck granules

Question 7

Markers of LAngerhans cells

Answer 7

S-100
CD 1a
CD 207

Question 8

Melanocyte is present in

Answer 8

Stratum basale

Question 9

Markers of melanocyte

Answer 9

S-100
Melan- A
HMB-45

Question 10

Merkel cells are present in

Answer 10

St. Basale

Question 11

Marker of merkel cell

Answer 11

Cytokeratin-20

Question 12

Neutrophilic micro abscess is seen in

Answer 12

Psoriasis- Monroe microabscess ( st. Corneum)
-spongiform pustule of kogoj (st. Spinosum)
Dermatitis herpetiformis - papillary tip microabscess

Question 13

Eosinophilic microabscess is seen in

Answer 13

Pemphigus vegetans

Question 14

Atypical T cell abscess is seen in

Answer 14

Pautrier microabscess- ctcl

Question 15

Petechiae size is

Answer 15

1-2mm

Question 16

Purpura size Is

Answer 16

> 3mm

Question 17

Ecchymoses size is

Answer 17

1-2cm

Question 18

Erosion is

Answer 18

Loss of epidermis

Question 19

Ulcer is

Answer 19

Loss of epidermis plus partial dermis

Question 20

LANGERS line corresponds to

Answer 20

Orientation of collagen fibres in the skin

Question 21

BLASCHKOS lines correspond to

Answer 21

Represent lines of embryological development

Question 22

True NIKOLSKY sign is seen in

Answer 22

Pemphigus foliaceus
Pemphigus vulgaris
SSSS

Question 23

DIASCOPY in Lupus vulgaris

Answer 23

Apple jelly nodules

Question 24

Desmosomes are targeted in which diseases

Answer 24

Pemphigus
Bullous impetigo
Hsv 
Ssss
Hailey hailey disease
Darier disease

Question 25

Lichenification is characterised by

Answer 25

Hyper pigmentation Thickening of Skin Exaggerated skin markings

Question 26

Layers of hair

Answer 26

``` Hair shaft Inner root sheath Outer root sheath Glassy membrane Connective tissue sheath ```

Question 27

Epidermis is derived from

Answer 27

Ectoderm

Question 28

Dermis is derived from

Answer 28

Mesoderm

Question 29

Lamellar granules are present in

Answer 29

St granulosum

Question 30

Desmosomes aka

Answer 30

Macula adherens

Question 31

Protein present in desmosomes

Answer 31

Desmoglein Desmocollin Desmoplakin

Question 32

Meissner corpuscle is present in

Answer 32

Papillary dermis

Question 33

Superficial vascular plexus of skin is present

Answer 33

Below papillary dermis | I.e btw papillary and reticular dermis

Question 34

Deep vascular plexus is present

Answer 34

Below reticular dermis

Question 35

Connective tissue of reticular dermis

Answer 35

Dense irregular

Question 36

Ratio of type 1 : type 3 collagen

Answer 36

8:1

Question 37

The colour of skin does not depend on

Answer 37

No. Of melanocyte

Question 38

2 types of melanin

Answer 38

Eumelanin | Pheomelanin

Question 39

Eumelanin is

Answer 39

Brown black pigment | Present in dark skin people

Question 40

Pheomelanin is

Answer 40

False melanin Yellow-red pigment Present in fair people

Question 41

Merkel cells aka

Answer 41

Haascheiban cells

Question 42

hemidesmosomal protein

Answer 42

BPag 1,2 K5/K14 Plectin

Question 43

Anchoring filaments proteins

Answer 43

Laminitis 5/332 Type 4 collagen Nidogen

Question 44

Anchoring fibrils protein

Answer 44

Collagen 7

Question 45

Tzanck smear is fixed using

Answer 45

Formal-zenker solution

Question 46

Tzanck smear stain used

Answer 46

Giemsa

Question 47

Cutaneous pigmentation with telengiectasis is known as

Answer 47

Poikiloderma

Question 48

Indications for PUVA therapy

Answer 48

``` Psoriasis Atopic dermatitis Vitiligo Polymorphic light eruption CTCL ```