Hirsutisme, hypertrichose Flashcards

1
Q

DDX hirsutisme?

A

excès androgènes

ovaire:
SPOK
idiopathique
tumeur ovarienne ex. Laydig-Sertoli cell

surr:
hyperplasie surr
Cushing
tumeur surrénalienne

rx:
Danazol
norgestrel-ethinyl estradiol

autre: hyperPRL

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2
Q

DDX hypertrichose?

A

idiopathique
rx: phenytoïne, minoxidil, cyclosporine

hypot4
malnutrition
malignité
dermatomyosite
hyperPRL
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3
Q

investigations hirsutisme?

A

testo
DHEAS
cortisol urinaire x24 h

selon pertience: 17-OHP

estrogène
FSH-LH si pertinent

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4
Q

conduite rx pour hirsutisme?

A
Co
sprionolactone
cypreoterone acetate
flutamide
5-alpha-reductase type 1 inhibitor
eflornithine (Vaniqa)

si déficit en 21-OH: cortico

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5
Q

investigation hirsutisme?

A

testo
DHEASPRL
cortisol sérique et urinaire
abdo TDM : avec ovaires et surrénales

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