Hipoglucemiantes Flashcards

1
Q

Grupo de sulfoniureas mas usado que a demas tiene una duracion corta

A

Glibenclamida, tolbutamida, gliquidona, glicliclamida

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2
Q

Mecanismo de las sulfoniureas

A

Pancreas bloquea katpasa que permitenroningreso de calcio, liberacion de insulina, inhibe glucojeogenesis y aumenta el consumo de glucosa, debe tomarse media hora antes de comer

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3
Q

Hipoglucemia, anemia aplasica, teratogeno, diarrea, hiponatremia y aumento de peso son efectos secundarios de que grupo de farmacos

A

Sulfoniureas

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4
Q

Medicamento de primera eleccion en px con dm2 leve y obesos

A

Metformina de la familia de biguanida

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5
Q

Mecanismo de biguanida

A

Estimula la perdida de peso, incrementa alanina glicerol y acido lactico

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6
Q

Efecto secundario de la metformina

A

Acidosis lactica y anorexia por el sabor metalico

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7
Q

Cuales son los farmacos inhibidores de la alfa glucosidasa

A

Migitol y acarbosa

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8
Q

Mecanismo de los inhibidores de alfa glucosidasa

A

Inhibicion irreversible, no sltera secrecion de insulina, administrar con comidas, no en embarazadas, lactsncia ni mal transito intestinal

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9
Q

Caracteristica del migitol y acarbosa y su efecto secundario

A

Migitol: coadyudante
Acarbosa: tx primera linea dm2

Efecto secundario: mala absorcion, flatulencia, se se da sola causa hipoglucemia

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10
Q

Troglitazona, pioglitazona y ciglitazona son parte de que grupo

A

Tiazolidionas

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11
Q

Px que no tolera a metformina que le recetas?

A

Pioglitazona

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12
Q

Mecanismo de las tiazolidonas

A

Incrementa sensibilidad a insulina, inhibe gluconeogenesis, extrecion biliar, baja microalbumina, no causa hipoglucemia

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13
Q

Efecto secundario de la tiazoldionas

A

Gastricas, cardiomegalia, edema, anemia y aumento de peso

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14
Q

Farmacos que forman parte del grupo de sulfonilureas

A
  1. Giblencamida, tolbutamida, gliquidona, glicliclamida
  2. Gliclazida, acetohexamida, glibormurida, gliburida, glimepirida, glipizida
  3. Cloropropramida
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