Hindlimb Flashcards
what is integument?
skin
what are the main functions of integument?
thermoregulation, secretion, sensory input, pigmentation, vitamin D metaolism
what is thermoregulation?
the ability of an organism to keep its body temperature within certain boundaries, even when the surrounding temperature is very different
what parts of the body are the core temperature?
brain, thorax and abdomen
what happens to temperature after a normal increase in metabolic rate?
increase in temp
Describe the negative feedback loop for temperature
change in temp/body heat production change in body temp change in thermosensors change in hypothalamic activity altered heat loss/production body temp returns to normal range
what is the sacrotuberous ligament called in horses?
broad ligament
what is the difference in the sacrotuberous ligament in dogs and cats?
absent in cats
what muscles arise from the sacrotuberous ligament?
bicep femoris, superficial gluteal, piriformis and tenuissimus
where does the biceps femoris insert?
by way of aponeurosis over the proximal stifle region onto the tibial tuberosity, further aponeurosis and small tendon also contribute to the calcanean tendon
what is the action of the biceps femoris?
flexion and extension of the stifle, extension of the hock
what is the innervation of the bicep femoris?
ischiatic nerve
where is the femoral triangle?
proximal medial thigh
what are the boundaries of the femoral triangle?
caudal edge of caudal belly or sartorius, cranial edge of pectineus, iliopsoas
what important structures lie within the femoral triangle?
VAN - vein, artery nerve
femoral region so femoral VAN
which of the femoral VAN lies most caudally?
femoral vein most caudal, femoral vein is most cranial
do the femoral VAN lie superficially or deep within the femoral triangle?
superficially
what muscle does the femoral nerve supply?
sartorius and quadriceps
what are the GAPE muscles?
gracillis, adductors, pectineus, external obturator muscles
what cutaneous area does the femoral nerve supply?
doesn’t directly supply any cutaneous area
supplied by the saphenous branch of the femoral nerve
what area of the skin does the femoral nerve supply?
caudal/plantar leg, crus and pes
what area of skin does the saphenous nerve supply?
medial leg, crus and pes
is there a saphenous artery/vein on the medial aspect of the crus?
yes
medial and lateral branches of both artery and vein
how many heads does the gastrocnemius have?
2 heads - one medial and one lateral
which bony structures might be associated with the heads of the gastrocnemius?
the fabellae - one medial and one lateral
where does the gastrocnemius insert?
by way of strong tendon onto the calcanean tuberosity
gastrocnemius tendon initially lies superficial to the tendon of the SDFT, but then runs lateral and eventually deep to it to insert on the calcanean tuberosity
what is the innervation of the gastrocnemius muscle?
tibial branch of the ischiatic nerve
what does the sympathetic branch of the autonomic nervous system do to aid physiological thermoregulation?
changes in the blood supply to the skin and contracts the erector pili muscle
what are the the physiological thermoregulation responses?
autonomic nervous system, evaporative heat loss (panting and sweating), thermogenesis (shivering and non-shivering)
what is the role of the sympathetic nervous system in thermoregulation?
stimulates contraction of vascular smooth muscle controlling resistance in small blood vessels, stimulates contraction of erector pili muscle adjusting the insulating properties of fur and plumage by increasing thickness of trapped layer of air
what is the result of high ambient temperatures on sympathetic activity and what is the body’s response?
decreased sympathetic activity
relaxation of resistance arterioles so blood directed to the dermis through subcutaneous adipose tissue, bypassing insulation
erector pili muscle relaxed so less trapped air
what is the result of low ambient temperatures on sympathetic activity and what is the body’s response?
increased sympathetic activity
contraction of resistance arterioles, reduced blood flow in dermis and subcutaneous fat layer provides insulation against heat loss from vasculature
erector pili contracts, stands hairs up and increases trapped air in fur, providing further insulation
what is the order of species in regards to their normal core temperatures from low to high?
horse, cow/ox, pig, sheep, cat, dog
HOPS cat dog
which of the domestic species sweat the most?
horses sweat lots, cattle and sheep sweat moderately, pigs, dogs and cats sweat minimally
what do pigs, dogs and cats rely on most for evaporative heat loss?
panting
how does panting work?
rapid and shallow breathing that doesn’t go all the way down to the lungs, natural frequency of oscillation so relatively little energy expended, most of the water is coming from the nasal turbinates
will a panting dog develop a respiratory alkalosis?
no - panting doesn’t affect ventilation as it is only in the nasal turbinates
where does most energy generation take place in the body?
60-70% in the heart, brain, liver and kidney
how much energy is converted to heat during voluntary exercise?
80%
what is the shivering method of thermogenesis?
primary involuntary means of increasing heat production
antagonistic muscles contract simultaneously
what is the non-shivering method of thermogenesis?
increases basal metabolic rate by increasing thyroid hormone levels and in brown fat (skeletal muscle)
when is brown fat important for an animal and how do brown fat levels change as the animal ages?
important for lambs- 40% of heat production
important for hibernating animals
thought to disappear in adults/as the animal changes- some evidence emerging to suggest otherwise
what does thyroid hormone do?
causes slow-developing prolonged increase in metabolism
what does an increase in the secretion of thyroid hormones do to metabolic rate?
increases
what happens if an animal reaches the lower critical temperature of the thermoneutral zone (TNZ)?
animal must start heat production to maintain body temperature
what happens in an animal reaches upper critical temperature of the thermo neutral zone (TNZ)?
cutaneous blood flow has reached its maximum and extra energy is required for losing heat
how does an adult animals LCT and TNZ compare to that of a neonate?
lower LCT and wider TNZ
what is the name of vitamin D3?
cholecalciferol
where is vitamin D3 synthesised?
in the skin
describe vitamin D synthesis
7-dehydrocholesterol (7-DHC) interacts with sun to make cholecalciferol
what inhibits vitamin D synthesis?
dense fur coat and heavy pigmentation
what are the three stages of hair growth?
anagen (growing phase), catagen (transition phase with regression of the lower part of the hair follicle) and telogen (resting phase)
what affects the hair growth cycle?
genetic, age, hormones
when do most animal shed their coat?
seasonally- with the photoperiod
which hormones influence shedding of the coat?
prolactin and melatonin
how does photoperiod influence hair loss?
photoperiod references the length of the day and night
melatonin is produces in the dark
longer nights = more melatonin production = more shedding
how does an decrease in thyroid hormone impact hair growth/loss?
decreased time spent in anagen so less hair growth
increased times spent in telogen so increased hair loss
what do sebaceous glands do?
secrete sebum oil
what is the function of sebum?
oils hairs
forms an oily film on the skin that
retards water loss, lubricates skin, inhibits growth of certain bacteria, helps spread sweat, territorial marker for some animals
how is sebum secreted onto the skin?
escapes during piloerection as contractions of the piloerector muscle squeeze the gland
how is water resistance of the skin improved?
sebaceous gland secretions (lipids)
insoluble keratin within keratinocytes
how are sebaceous glands regulated?
regulated by sex steroid hormones
more active after puberty
larger and more productive in the breeding season
do birds have sebaceous glands?
none within feathers
during preening birds spread secretions from a gland at the base of their tail
what is the sebaceous gland at the base of a birds tail called?
uropygial gland
where are specialised skin glands found? (3 examples)
anal sacs in dogs and cats
interdigital pouch of sheep
infraorbital pouch of sheep
tail glands of dog
why is melanin production important?
camouflage, mimicry, social communication, protection against harmful effects of solar radiation
what is the function of melanocytes?
synthesis and package vesicles of melanin, intact vesicles are transferred into keratinocytes
when the keratinocytes reach the surface of the skin melanin is shed
what are the two pigments of melanin?
eumelanin (black and brown) and pheomelanin (red and yellow)
what can affect pigment synthesis?
genetics, local factors of the skin, hormones
describe the synthesis of melanin
melanin synthesising hormone (MSH) outside the cell binds to a MSH receptor in the cell membrane, reactions inside the cell result in pigment production
what stimulates the production of melanin synthesising hormone (MSH)?
UV light disease states (cushings syndrome) other external signals (camouflage)
what are keratinocytes?
main cells in the epidermis, stem cells in the stratum basale
what are melanocytes?
dispersed between basal cells, produce pigment (melanin)
what are Langerhans cells?
monocytes-derived dendritic cells, immuno-surveillance cells, important in antigen presentation