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pharm exam 3 > Hill's deck of death > Flashcards

Hill's deck of death Flashcards

1
Q

Antacids

A
  • prevents gastric ulcerations
  • frequent administration is needed!
  • divalent cations inhibit enrofloxacin absorption
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2
Q

Ranitidine

A
  • prevents gastric ulcerations
  • H2 inhibitor
  • has slight interference with P450 in liver + prokinetic (muscarinic agonist)
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3
Q

Famotidine

A
  • prevents gastric ulcerations

- H2 inhibitor

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4
Q

Omeprazole

A
  • prevents gastric ulcerations

- H:K ATPase inhibitor

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5
Q

Pantoprazole

A
  • prevents gastric ulcerations
  • H:K ATPase inhibitor
  • IV so good to give to anorexic patients
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6
Q

Lansoprazole

A
  • prevents gastric ulcerations
  • H:K ATPase inhibitor
  • formulated with HCO3 as an oral liquid for small dogs
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7
Q

Sucralfate

A
  • prevents gastric ulcerations
  • mucosal coating chelating and complexing agent
  • converted into sugar by acid that coats stomach lesions, once activated it coats the stomach
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8
Q

Cisapride

A
  • prevents gastric ulcerations
  • prokinetic (mixed 5HT3 antagonist and 5HT4 agonist)
  • enhances motility in stressed patients or patients treated with steroids
  • used to stop gastric reflex
  • promotes release of Acetyl choline from myenteric plexus throughout smooth muscle of the small intestine
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9
Q

Apomorphine

A
  • induce emesis
  • D2 agonist (works on CTZ)
  • does not work in cats, CTZ does not do as good as job in cats
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10
Q

Xylazine

A
  • induce emesis
  • adrenergic agonist (works on vomiting center directly)
  • used in cats
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11
Q

Dexmeditomidine

A
  • induce emesis
  • adrenergic agonist (works on vomiting center directly)
  • used in cats
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12
Q

Diphenhydramine

A
  • Antiemetic
  • Works on CTZ by H1 inhibition
  • prevents motion sickness
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13
Q

Centrine

A
  • Antiemetic

- non-specific antimuscarinic for motion sickness

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14
Q

Chlorpromazine

A
  • Antiemetic

- Alpha 2 antagonist

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15
Q

Prochlorperazine

A
  • Antiemetic

- Alpha 2 antagonist

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16
Q

Acepromazine

A
  • Antiemetic

- Alpha 2 antagonist

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17
Q

Maropitant

A
  • Antiemetic
  • NK1 receptor antagonist
  • works on vomiting center
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18
Q

Metoclopramide

A
  • Antiemetic
  • dopamine antagonist also (5HT3)
  • only acts on CTZ
  • crosses BBB
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19
Q

Ondansetron

A
  • Antiemetic
  • 5HT3 antagonist
  • works on CTZ and vagal efferents from stomach
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20
Q

Mirtazapine

A
  • prokinetic

- mixed 5HT3 antagonist and 5HT4 agonist

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21
Q

Erythromycin

A
  • prokinetic
  • muscarinic agonist
  • motilin agonist
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22
Q

Lidocaine

A
  • prokinetic
  • muscarinic agonist
  • thoracic epidural analgesia for post-op ileus
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23
Q

Octreotide

A
  • prokinetic
  • muscarinic agonist
  • beneficial for ileus in one canine study
  • somatostatin (inhibits gastric secretion) analog
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24
Q

Loperamide

A
  • antidiarrheal
  • morphine agonist with weak central action (Mu receptors are promoted to increase segmental contraction and not propagated contraction, which slows transit and aids absorption)
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25
Q

Diphenoxalate

A
  • antidiarrheal
  • morphine agonist with weak central action (Mu receptors are promoted to increase segmental contraction and not propagated contraction, which slows transit and aids absorption)
  • also inhibits secretion
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26
Q

Kaolin

A
  • antidiarrheal

- absorbant (but dsnt actually help with anything, just makes poop look ok)

27
Q

Attapulgite

A
  • antidiarrheal

- absorbant (but dsnt actually help with disease, just makes poop look ok)

28
Q

Dioctahedral Smectite

A
  • antidiarrheal

- absorbant (but dsnt actually help with disease, just makes poop look ok)

29
Q

Activated Charcoal

A
  • antidiarrheal
  • absorbant (but dsnt actually help with disease, just makes poop look ok)
  • routine treatment for poisoning
30
Q

Enrofloxacin

A
  • antibiotic

- for Boxer colitis

31
Q

Tetracycline

A
  • antibiotic

- for small intestine dysbiosis

32
Q

Metronidazole

A
  • antibiotic

- for small intestine dysbiosis

33
Q

Tylosin

A
  • antibiotic

- for small intestine dysbiosis

34
Q

Enterococcus faecium

A

-probiotic

35
Q

Bifidobacterium animalis

A

-probiotic

36
Q

Oligosaccharides

A

-prebiotic

37
Q

Soluble fiber

A
  • prebiotic

- Ex: pectin and gums

38
Q

beet pulp

A
  • prebiotic

- combined soluble and insoluble fiber

39
Q

Prednisone/Prednisolone

A

-corticosteroid

40
Q

Dexamethasone

A
  • corticosteroid

- about 7x stronger then Prednisone

41
Q

Budesonide

A
  • corticosteroid

- first past effect through liver

42
Q

Azathioprine

A

-purine analog

43
Q

Cyclophosphamide

A

-alkylating agent

44
Q

Chlorambucil

A

-alkylating agent

45
Q

Cyclosporine

A
  • anti-inflammatory

- modifies cell mediated immunity (for anal fistulas)

46
Q

Leflunamide

A

-immunomodulator

47
Q

Mycophenolate mofetil

A

-suppresses T cells by inhibiting purine synthesis

48
Q

Sulfasalazine

A
  • Aminosalicylates

- anti-inflammatory/ antibiotic used to treat colitis

49
Q

Olsalazine

A

-Aminosalicylates

50
Q

Bismuth subsalicylate

A

-Aminosalicylates

51
Q

Magnesium sulfate

A
  • laxative

- osmotic agent

52
Q

Colyte

A
  • laxative
  • osmotic agent
  • used to prep colon for colonoscopy
53
Q

Methylcellulose

A
  • laxative

- soluble fiber

54
Q

Psyllium

A
  • laxative

- soluble fiber

55
Q

Pumpkin

A
  • laxative
  • soluble fiber
  • used in cats
56
Q

Lactulose

A
  • laxative

- indigestible sugar

57
Q

Mineral Oil

A
  • laxative
  • lubricant
  • risk of inhalation pneumonia
58
Q

Petrolatum

A
  • laxative

- lubricant

59
Q

Dioctyl sodiium sulphosuccinate

A
  • laxative

- emolient

60
Q

Fenbendazole

A

-parasitic drug for roundworm

61
Q

Pyrantel

A

-parasitic drug for roundworm

62
Q

Praziquantel

A

-parasitic drug for tapeworm

63
Q

Ponazuril

A

-coccidiostats (treats coccidia)

pharm exam 3 (6 decks)

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