Hill's deck of death Flashcards
1
Q
Antacids
A
- prevents gastric ulcerations
- frequent administration is needed!
- divalent cations inhibit enrofloxacin absorption
2
Q
Ranitidine
A
- prevents gastric ulcerations
- H2 inhibitor
- has slight interference with P450 in liver + prokinetic (muscarinic agonist)
3
Q
Famotidine
A
- prevents gastric ulcerations
- H2 inhibitor
4
Q
Omeprazole
A
- prevents gastric ulcerations
- H:K ATPase inhibitor
5
Q
Pantoprazole
A
- prevents gastric ulcerations
- H:K ATPase inhibitor
- IV so good to give to anorexic patients
6
Q
Lansoprazole
A
- prevents gastric ulcerations
- H:K ATPase inhibitor
- formulated with HCO3 as an oral liquid for small dogs
7
Q
Sucralfate
A
- prevents gastric ulcerations
- mucosal coating chelating and complexing agent
- converted into sugar by acid that coats stomach lesions, once activated it coats the stomach
8
Q
Cisapride
A
- prevents gastric ulcerations
- prokinetic (mixed 5HT3 antagonist and 5HT4 agonist)
- enhances motility in stressed patients or patients treated with steroids
- used to stop gastric reflex
- promotes release of Acetyl choline from myenteric plexus throughout smooth muscle of the small intestine
9
Q
Apomorphine
A
- induce emesis
- D2 agonist (works on CTZ)
- does not work in cats, CTZ does not do as good as job in cats
10
Q
Xylazine
A
- induce emesis
- adrenergic agonist (works on vomiting center directly)
- used in cats
11
Q
Dexmeditomidine
A
- induce emesis
- adrenergic agonist (works on vomiting center directly)
- used in cats
12
Q
Diphenhydramine
A
- Antiemetic
- Works on CTZ by H1 inhibition
- prevents motion sickness
13
Q
Centrine
A
- Antiemetic
- non-specific antimuscarinic for motion sickness
14
Q
Chlorpromazine
A
- Antiemetic
- Alpha 2 antagonist
15
Q
Prochlorperazine
A
- Antiemetic
- Alpha 2 antagonist
16
Q
Acepromazine
A
- Antiemetic
- Alpha 2 antagonist
17
Q
Maropitant
A
- Antiemetic
- NK1 receptor antagonist
- works on vomiting center
18
Q
Metoclopramide
A
- Antiemetic
- dopamine antagonist also (5HT3)
- only acts on CTZ
- crosses BBB
19
Q
Ondansetron
A
- Antiemetic
- 5HT3 antagonist
- works on CTZ and vagal efferents from stomach
20
Q
Mirtazapine
A
- prokinetic
- mixed 5HT3 antagonist and 5HT4 agonist
21
Q
Erythromycin
A
- prokinetic
- muscarinic agonist
- motilin agonist
22
Q
Lidocaine
A
- prokinetic
- muscarinic agonist
- thoracic epidural analgesia for post-op ileus
23
Q
Octreotide
A
- prokinetic
- muscarinic agonist
- beneficial for ileus in one canine study
- somatostatin (inhibits gastric secretion) analog
24
Q
Loperamide
A
- antidiarrheal
- morphine agonist with weak central action (Mu receptors are promoted to increase segmental contraction and not propagated contraction, which slows transit and aids absorption)
25
Diphenoxalate
- antidiarrheal
- morphine agonist with weak central action (Mu receptors are promoted to increase segmental contraction and not propagated contraction, which slows transit and aids absorption)
- also inhibits secretion
26
Kaolin
- antidiarrheal
| - absorbant (but dsnt actually help with anything, just makes poop look ok)
27
Attapulgite
- antidiarrheal
| - absorbant (but dsnt actually help with disease, just makes poop look ok)
28
Dioctahedral Smectite
- antidiarrheal
| - absorbant (but dsnt actually help with disease, just makes poop look ok)
29
Activated Charcoal
- antidiarrheal
- absorbant (but dsnt actually help with disease, just makes poop look ok)
- routine treatment for poisoning
30
Enrofloxacin
- antibiotic
| - for Boxer colitis
31
Tetracycline
- antibiotic
| - for small intestine dysbiosis
32
Metronidazole
- antibiotic
| - for small intestine dysbiosis
33
Tylosin
- antibiotic
| - for small intestine dysbiosis
34
Enterococcus faecium
-probiotic
35
Bifidobacterium animalis
-probiotic
36
Oligosaccharides
-prebiotic
37
Soluble fiber
- prebiotic
| - Ex: pectin and gums
38
beet pulp
- prebiotic
| - combined soluble and insoluble fiber
39
Prednisone/Prednisolone
-corticosteroid
40
Dexamethasone
- corticosteroid
| - about 7x stronger then Prednisone
41
Budesonide
- corticosteroid
| - first past effect through liver
42
Azathioprine
-purine analog
43
Cyclophosphamide
-alkylating agent
44
Chlorambucil
-alkylating agent
45
Cyclosporine
- anti-inflammatory
| - modifies cell mediated immunity (for anal fistulas)
46
Leflunamide
-immunomodulator
47
Mycophenolate mofetil
-suppresses T cells by inhibiting purine synthesis
48
Sulfasalazine
- Aminosalicylates
| - anti-inflammatory/ antibiotic used to treat colitis
49
Olsalazine
-Aminosalicylates
50
Bismuth subsalicylate
-Aminosalicylates
51
Magnesium sulfate
- laxative
| - osmotic agent
52
Colyte
- laxative
- osmotic agent
- used to prep colon for colonoscopy
53
Methylcellulose
- laxative
| - soluble fiber
54
Psyllium
- laxative
| - soluble fiber
55
Pumpkin
- laxative
- soluble fiber
- used in cats
56
Lactulose
- laxative
| - indigestible sugar
57
Mineral Oil
- laxative
- lubricant
- risk of inhalation pneumonia
58
Petrolatum
- laxative
| - lubricant
59
Dioctyl sodiium sulphosuccinate
- laxative
| - emolient
60
Fenbendazole
-parasitic drug for roundworm
61
Pyrantel
-parasitic drug for roundworm
62
Praziquantel
-parasitic drug for tapeworm
63
Ponazuril
-coccidiostats (treats coccidia)