Higher Order cerebral Function Flashcards

1
Q

Describe the organization of fibers traveling with visual information from the lateral
geniculate nucleus to the occipital lobe. How are they, and their destinations, organized?

A
superior striations (go to the parietal lobe) provide retinal input for inferior 
inferior striations (to temporal lobe)  with retinal input from superior
; the more central the field, the more caudal and closer it is to the occipital pole
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2
Q

what is a key feature of the occipital pole blood supply as opposed to the rest of the visual cortex?

A

bilateral vascularization

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3
Q

what type of damage would result in central scotoma? Describe what this looks like.

A

blindness in acuity/focal point of one eye; damage to the fovea of that eye

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4
Q

what type of damage would result in monocular blindness?

A

damage to that eye’s optic nerve, one-eyes blindness

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5
Q

Describe bitemporal hemianopia. What might cause this?

A

damaged optic chiasm> commonly caused by pituitary tumors; blindness on the lateral visual fields

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6
Q

Describe homonymous hemianopia. What might cause this?

A

damage to the contralateral optic tract or thalamus; hemified blindness in each eye on the same side

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7
Q

Describe superior quadrantanopia . What might cause this?

A

damage to inferior striations (in the temporal lobe) in contralateral side> upper quadrant blindness in the opposite side of injury

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8
Q

Describe inferior quadrantanopia. What might cause this?

A

damage to superior striations (in the temporal lobe) in contralateral side> lower quadrant blindness on the opposite side of injury

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9
Q

Describe homonymous hemianopia with macular sparing. What might cause this?

A

damage to the contralateral primary visual cortex but due to bilateral vascularization of the occipital pole > blindness in the same side of both eyes

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10
Q

Where are the visual association cortices located?

A

parieto-occipital association cortex

occipitotemporal association cortex

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11
Q

what kind of info is relayed through the parieto-occipital association cortex?

A

motions and spatial relationships between objects, body, and visual stimuli (where)

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12
Q

what kind of info is relayed through the occipitotemporal association cortex?

A

form, colors, face, letters,etc (what)

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13
Q

What types of eye movements do supranuclear structures of extraocular muscles control?

A
horizontal and vertical eye movements
saccades
smooth pursuits
vergence 
reflexes
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14
Q

Identify the supranuclear structures and connections involved horizontal eye movements.

A

medial and lat rectus (abducens and OCM via MLF)

abducens + paramedian pontine reticular formation

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15
Q

Identify the supranuclear structures and connections involved vertical eye movements.

A

muscles: superior and inf recti and obliques
nuclei: trochlear and OCM
supranuclear: pretectal areas, rostral midbrain and reticular formation

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16
Q

saccades

A

rapid, voluntary eye movements wherein our vision is temporarily suppressed

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17
Q

smooth pursuit

A

slow following of a visual target either voluntarily or involuntarily

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18
Q

vergence

A

maintaining fused fixation as targets move towards or away from the person-very slow for acuity

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19
Q

reflexive eye movements: Nystagmus

A

eyes one way to self correct

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20
Q

What cortical structures are involved in extraocular movements?

A

frontal eye fields (contra saccades), parietal-occipital-temporal cortex (ipsa smooth pursuit), basal ganglia (OCM loop)

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21
Q

define unimodal association cortices

A

unidirectional and modality-specific: Motor, somatosensory, Visual and Auditory

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22
Q

define heteromodal association cortices

A

bidirectional and higher-order mental functions found at frontal and parieto-occipitotemporal junctions

23
Q

Explain what we know about handedness and how it relates to cortical asymmetry.

A

each hemisphere controls simple movements of contralat limbs, but highly skilled and complex movements are controlled by the dominant hemisphere

24
Q

Explain what we know about language centers as they relate to cortical asymmetry.

A

language centers are predominantly on the left hemisphere (regardless of handedness) for 95% R and over 70% L (also bilateral in many lefthanders)

25
Where can Broca’s area be found? What is its function?
inferior frontoparietal area allows the motor formation of words via sounds
26
Where can Wernicke’s area be found? What is its function?
superior temporal lobe. comprehension of words from the sound
27
How are Broca’s and Wernicke’s areas connected?
via arcuate fasciculus along the sylvian fissure
28
What other dominant hemisphere structures are involved in language processing?
inf lateral primary cortex frontal lobe <>Broca's (syntax, motor aspects, planning) supramarginal gyrus and angular gyrus <>wernicke's (lexicon and writing) the visual cortex, visual assn areas
29
How does the non-dominant hemisphere get involved in language processing?
involved with the affective elements of speech (tone) via the corpus callosum
30
What subcortical structures play a role in language processing, and what is that role?
thalamus and basal ganglia >> can change projection or cadence of speech
31
Define aphasia
impacts DOMINANT structures (typically left) | disturbance of one or more aspects of the production and comprehension of speech
32
Broca’s aphasia
"motor aphasia" | effortful speech + awareness of deficits
33
Wernicke's Aphasia
impaired language comprehension + unaware of deficits
34
Global Aphasia
Broca's + Wernicke's impairments
35
What is alexia and what can it look like?
reading impairment w/ Broca's aphasia: hard time reading aloud w Wernicke's aphasia: nonsense
36
What is agraphia and what can it look like?
impairment in writing w/ Broca's aphasia: effortful or fragmented w Wernicke's aphasia: nonsense
37
What is our non-dominant hemisphere best known for as it relates to cortical asymmetry?
PERCEPTUAL INTEGRATION visual-spatial skills emotional significance music perception
38
Define perception. What are the four components of perception often included in a neuro exam?
using info from senses to interact with the environment | body schema, spatial relationships, agnosias, apraxias
39
Explain the difference between body schema and body image.
image is conscious thoughts about won body vs schema: unconscious motor/postural control and relationships of body parts to each other (body awareness)
40
What is unilateral inattention? What type of lesions are typically responsible?
failure to acknowledge stimuli on the side contralateral to the lesion (left most common) despite other systems being unimpaired MOSTLY W/ R TEMPOROPARIETAL JUNCTION, POST PARIETAL LESIONS
41
What are the 2 classification systems for unilateral attention?
Modality or Distribution
42
list the modality types of unilateral inattention
sensory, motor, representational (internal images)
43
list the distribution types of unilateral inattention
personal- lack of awareness of the contralateral side of body spatial- lack awareness in contralat space -peripersonal: w/in arms reach -extrapersonal: in far space
44
Define position-in-space disorder
decreased ability to perceive and interpret prepositional positions
45
Define vertical/midline disorientation and provide an example:
can't identify when the body is in midline , ex:pusher's disorder
46
Define topographical disorientation.
difficulty perceiving relationships from one location to another in the environment
47
What are agnosias? What are the different types commonly seen?
decreased ability to recognize stimuli when the sensory system is INTACT visual, auditory (inability to rec nonspeech), tactile (astereognosis and agraphesthesisa)
48
Describe asomatognosia.
loss of ownership or perceived agency over a limb
49
Describe anosognosia.
severe* | denial or lack of awareness of presence or severity of deficits can demonstrate astereognosis
50
What is apraxia? What are the two major subtypes?
impairment of voluntary skilled movement w/ deficit in left (dominant) frontal or parietal lobe ideomotor and ideational
51
How do ideomotor and ideational apraxia differ?
ideomotor: breakdown between concept and performance (right idea, wrong action) ideational: failure in conceptualization
52
What is the function of the prefrontal cortex?
executive function: decision-making, problem-solving, self-control, longterm goal execution
53
What are the different regions of the prefrontal cortex
dorsolateral-switching attn. inhib inappropriate response, maintaining abstract rules (good employee) orbitofrontal- DECISONS ventromedial- emotional processing, short term mem, self perception and social cognition
54
Describe some of the different ways in which the prefrontal cortex is involved in restraint, initiative, and order.
restraint: judgment, foresight, discipline initiative: curiosity, flexibility, drive order: abstract reason, sequencing, working memory, organize