High yield random stuff

Question 1

How many babies are affected with a major structural abnormality?

Answer 1

2-4%

Question 2

What week is MSS1?

Answer 2

11-14 weeks

Question 3

What week is MSS2

Answer 3

14-20 wks

Question 4

What weeks can you have NIPT? +ves and -ves?

Answer 4

10+ weeks.
+ves: tells you about trisomies, can look at sex.

-ves: not funded.
false positives re: placental site mosacism

Question 5

What do bloods check MSS1:

Answer 5

PAPP-A and HCG

Question 6

What do bloods check MSS2

Answer 6

bHCG, inhibin A, AFP, uE3

Question 7

Specific risk factors for placental insufficiency/fetal demise?

Answer 7

Preeclampsia, SGA, diabetes, genetic abnormalities, smoking, age, high BMI, prev poor obstetric history

Question 8

What do maternal bloods done post- intrauterine death look for?

Answer 8

HbA1c, thrombophilia, antiphospholipid syndrome, infections, antibody screen, Kleihauer (mixing of fetal and maternal blood)

Question 9

How to manage future pregnancies in a woman with a prev IUGR?

Answer 9

?low dose aspirin from first trimester,
+ can do a doppler at 20 weeks to triage how often you need to do growth scans

Question 10

Causes of PPH

Answer 10

tone, tissue (RPOC), trauma or thrombus (Coag issue such as DIC)

Question 11

How does past med hx impact on PPH management?

Answer 11

Asthma - no F2 alpha
HTN - no ergometrine