high yield bone, joints, soft tissue Path Flashcards
radiograph: decreased cortical thickening
Osteoporosis
radiograph: diffuse, dense bone
Osteopetrosis
Radiograph: thickening of calvarium
Osteitis deformans (Paget disease of bone)
Xray: irregular lucencies with adjacent sclerosis
MRI: dark serpiinous necrotic bone
Osteonecrosis
bamboo spine
Ankylosing spondylitis
X ray: Soap bubble appearance
Giant cell tumor
X ray: Exotosis of bone
Osteochondroma
X ray: sun burst pattern/Codman triangle around metaphysis of long bones
Osteosarcoma
X ray: “onion skin” around diaphysis of long bone
Ewing sarcoma
Osteoporosis is dysfunction of what cell
osteoblast
Dowager’s hump: increased cervical lordosis and dorsal kyphosis
osteoporosis
Osteopetrosis is dysfunction in what cells
osteoclasts
Gene for osteopetrosis
Carbonic anhydrase
gene for Paget Disease
SQSTM1
what labs elevated in Paget disease of bone
Alk Phos
increase in hat size
Paget disease
Osteonecrosis of femoral head. what artery
medial circumflex femoral artery
HLA associated with Ankylosing spondylitis
HLA-27
cartilage capped tumor that is attached to underlying skeleton by bony stalk
osteochondroma
Herbeden nodes and Bouchard nodes
OA
Swan neck deformity and Boutonneire’s deformity
RA
genetic factors for RA
- HLA-DRB1
- PTPN22
antibodies against citrullinated peptides
RA
highlights for Juvenile idiopathic arthritis
- before 16
- lasts at least 6 weeks
- more common in large joints
- Absent RF and rheumatoid nodules
- ANA+