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PBL 2 Pharm > High Yield > Flashcards

High Yield Flashcards

1
Q

Anemia caused by trimethoprim

A

Megaloblastic anemia

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2
Q

Anti-bacterials that cause hemolysis in G6PD-deficient patients

A

Sulfonamides

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3
Q

Anti-emetics used in association with anti-cancer drugs that are 5-HT3 (serotonin receptor subtype ) antagonist

A

Odansetron, granisetron, dolasetron, palonosetron

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4
Q

Blows DNA (breaks DNA strands), limiting SE in pulmonary fibrosis

A

Bleomycin

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5
Q

Common side effect of Rifampin

A

Orange urine discoloration

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6
Q

DOC for bipolar affective disorder

A

Lithium

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7
Q

DOC for giardia, bacterial vaginosis, pseudomembranous colitis, and trichomonas

A

Metronidazole

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8
Q

DOC for herpes and its MOA

A

Acyclovir; activated by viral thymidine kinase, results in inhibition of viral DNA replication

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9
Q

DOC for influenza A and B

A

Oseltamivir or Zanamivir

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10
Q

DOC for N. gonorrhea

A

Ceftriaxone

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11
Q

DOC for RSV

A

Ribavirin

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12
Q

Drug used for MRSA

A

Vancomycin

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13
Q

HIV antiviral class known to have severe drug interactions by causing inhibition of metabolism

A

Protease inhibitors

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14
Q

May protect against doxorubicin cardio-toxicity by chelating iron

A

Dexrazoxane

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15
Q

Meningitis prophylaxis in exposed patients

A

Rifampin

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16
Q

MOA of sulfonamides

A

Inhibit dihydropteroate synthase

17
Q

Patients being treated with lithium, who are dehydrated, or taking diuretics concurrently, could develop

A

Lithium toxicity, lithium-induced nephrogenic diabetes insipidus

18
Q

SE of lithium

A

Tremor, sedation, ataxia, aphasia, thyroid enlargement, and reversible diabetes insipidus

19
Q

TCA used in chronic pain, enuresis, and OCD

A

Imipramine

20
Q

Technique used to diagnose perianal itching, and the drug used to treat it

A

Scotch tape technique
and mebendazole

21
Q

Treatment for TB patients (think RIPE)

A

Rifampin, Isoniazid, Pyrazinamide, and Ethambutol

22
Q

Unicyclic antidepressant least likely to affect sexual performance, used for management of nicotine withdrawal, SE’s include dizziness, dry mouth, aggravation of psychosis, and seizures

A

Bupropion

23
Q

Anti-estrogen used for estrogen receptor + breast cancer

A

Tamoxifen

24
Q

Binds tubulin and prevents the disassembly of microtubules during the M phase of the cell cycle inducing mitotic arrest

A

Paclitaxel (taxol)

25
Q

Cheap wide spectrum antibiotic DOC of otitis media

A

Amoxicillin

26
Q

Drug of choice for tx of pseudomembranous colitis

A

Metronidazole

27
Q

Interaction with this drug requires dose reduction of 6-MP

A

Allopurinol

28
Q

MOA of fluoroquinolones

A

Inhibit DNA gyrase (topoisomerase II) and topoisomerase IV

29
Q

Vancomycin MOA

A

Binds D-Ala-D-Ala on murein monomers and prevent polymerization of the murein monomers

PBL 2 Pharm (2 decks)

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