HIE Flashcards

1
Q

What is HIE caused by? [2]

A

intrapartum hypoxia and cerebral ischemia

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2
Q

what are the characteristics of HIE? [3]

A
  1. abnormal level of consciousness
  2. Abnormal tone
  3. Abnormal primitive reflexes
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3
Q

What are the other causes? [5]

Think of

A
  1. Brain malforming
  2. Haemodynamic instabillity
  3. Hypoglycemia
  4. Electrolyte disturbances
  5. Sepsis
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4
Q

intrapartum fetal hypoxia usually ends up causing?

Think of bilirubin encephalopathy

A

spastic quadriplegia and dyskinetic cerebral palsy

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5
Q

When does HIE occur?

A

First 2 days of life

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6
Q

When can therapeutic hypothermia be started?

Think of it as a dangerous and life-threatening situation

A

Within the first 6 hours of life

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7
Q

How to judge the severity of the encephalopathy

A
  1. Metabolic acidosis
  2. arterial cord with pH < 7
  3. severe encephalopathy during the first 48 hours of life
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8
Q

When do the signs increase and worsen? Between which hours?

A

48 hours to 72 hours

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9
Q

What is the Sarnat Stage?

A
  1. Irritability, increased tone, poor sucking BUT EXAGGERATED MORO REFLEX
  2. lethargy, decreased tone and primitive reflexes, seizures
  3. stupor or coma, flaccid tone, and fewer seizures
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10
Q

What causes the constant damage as the stages go up?

A

Reperfusion Injury

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11
Q

aEEG diagnoses?

A

subclinical seizures

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12
Q

Assessment and Management at birth

A
  • ABG
  • APGAR SCORE
  • check placenta
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13
Q

Respiratory System Management

A

can develop secondary surfactant deficiency and cerebral ischaemia

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14
Q

Cardiovascular Management

A

if Hb is less than 10g/dl consider blood transfusion

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15
Q

Fluid balances and electrolytes

A

SIADH, Intrinsic renal failure, and cerebral odema can occur
restrict fluid to 40 ml/kg/24 hours

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16
Q

if hypoglycemia occurs, how much glucose should be used for transfusion

A

12 -15%

17
Q

What is chorioamnionitis associated with?

Think why the amniotic fluid is cloudy?

A

intrapartum hypoxia

18
Q

hypothermia or hyperthermia for treatment and for how long

A

induced hypothermia no later than 6 hours

19
Q

Prognosis and Follow Up

A

Grade it with colours