HGA2 - Mitosis Flashcards

0
Q

Homologous chromosomes

A

a pair of chromosomes having the same gene sequence each derived from 1 parent
• not completely identical (different mutations)

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1
Q

Mitosis

A
  • nuclear division into 2 nuclei
  • results in 2 daughter cells identical to the parent nucleus
  • same number of chromosomes and genetic content as original cell
  • cytokinesis – division of rest of the cell
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2
Q

Centromere

A

attaches spindle fiber (motors up to poles)

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3
Q

Metacentric

A

centromere is in the middle

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4
Q

Acrocentric

A

centromere is closer to 1 end

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5
Q

Cell cycle

A

G1
S
G2
M

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6
Q

G1

A

interphase – 11 hours

gap before duplication

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7
Q

S

A

7 hours

DNA synthesis and chromosome duplication

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8
Q

G2

A

interphase - 4 hours

gap before mitosis

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9
Q

M

A
Mitosis – 2 hours
• prophase
• metaphase
• anaphase
• telophase
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10
Q

Centrosome

A
  • makes microtubules
  • organizes microtubules
  • contains 2 centrioles
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11
Q

Prophase

A
  • chromosomes condense
  • centrosomess move to opposite poles, new microtubules
  • nucleoli begin to disappear
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12
Q

Metaphase

A

• chromosomes align on metaphase plate with sister chromosomes facing opposite poles

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13
Q

Anaphase

A
  • centromeres split

* separated chromatids to opposite poles

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14
Q

Telophase

A
  • nuclear membrane and nucleoli re-form
  • spindle fibers disappear
  • chromosomes uncoil and become a tangle of chromatin
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15
Q

Cytokinesis

A
  • contractile ring

* cleavage furrow