Hexokinase vs Glucokinase Flashcards

1
Q

Has a considerably higher Km (lower affinity) for glucose

A

Glucokinase

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
2
Q

Present in most tissue

A

Hexokinase

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
3
Q

Its activity increases with increases in the concentration of glucose in the hepatic portal vein

A

Glucokinase

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
4
Q

Can phosphorylate glucose and other hexoses

A

Both Hexokinase and Glucokinase

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
5
Q

It acts to ensure an adequate rate of glycolysis to meet the liver’s needs

A

Hexokinase

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
6
Q

Present only in liver parenchymal cells and Islet cells of the pancreas

A

Glucokinase

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
7
Q

Has a low Km for glucose

A

Hexokinase

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
8
Q

High Vmax (Many enzymes) and Km (low affinity)

A

Glucokinase

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
9
Q

In the liver it is saturated and acting at a constant rate under all normal conditions

A

Hexokinase

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
10
Q

Liver activity induced by insulin

A

Glucokinase

How well did you know this?
1
Not at all
2
3
4
5
Perfectly